From NAFLD to MASLD Does the New Nomenclature Actually Change Care Review Abstract The transition from non alcoholic fatty liver disease to metabolic dysfunction associated steatotic liver disease represents a significant conceptual evolution in hepatology rather than a purely semantic change. Endorsed by major international
Endocrinology
Type 2 Diabetes Mellitus: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention
Type 2 Diabetes Mellitus as a Multifactorial Cardiometabolic Disease: Cellular Mechanisms, Reductionist Pitfalls, and Evidence-Based Prevention Narrative Review Abstract Type 2 diabetes mellitus (T2DM) is a progressive, heterogeneous, multi-organ metabolic disease characterized by chronic hyperglycemia arising from inadequate insulin secretion relative to metabolic demand, usually
Microplastics in Coffee Pods: Current Evidence and Potential Health Implications
Microplastics in Coffee Pods: Current Evidence and Potential Health Implications Key Takeaways Research reveals alarming levels of microplastic contamination in single-use coffee pods, with significant health implications for daily coffee drinkers and actionable solutions available. • A single plastic coffee pod can release over
The Microbiome and Metabolism: Can Gut Flora Be the Next Endocrine Organ?
The Microbiome and Metabolism: Can Gut Flora Be the Next Endocrine Organ? Abstract The human gut microbiome has increasingly been recognized as a central determinant of metabolic health, with growing evidence suggesting that it functions not merely as a collection of commensal microorganisms but as a
Obesity as Chronic Disease: Building a Follow-up Model Like HTN/A1c
Obesity as Chronic Disease Building a Follow-up Model Like HTNA1c Abstract Obesity is increasingly recognized as a chronic, relapsing, multifactorial disease that requires long term clinical management rather than episodic intervention. Its pathophysiology involves complex interactions among genetic predisposition, neuroendocrine regulation, metabolic adaptation, environmental
Thyroid Cancer Overdiagnosis: When Screening Causes More Harm Than Good
Thyroid Cancer Overdiagnosis When Screening Causes More Harm Than Good Abstract The incidence of thyroid cancer has risen substantially over the past three decades, drawing increased attention from clinicians, researchers, and public health authorities. Much of this rise has been attributed not to a true surge in aggressive
Why GLP-1 Receptor Agonists Are Becoming Essential Cardiovascular Drugs
Why GLP-1 Receptor Agonists Are Becoming Essential Cardiovascular Drugs Introduction Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have emerged as a transformative class of medications in the management of type 2 diabetes, demonstrating an approximate 14 percent reduction in major adverse cardiovascular events. Initially developed
Prediabetes Management in Family Practice: Comparative Effectiveness of Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy
Prediabetes Management in Family Practice Comparative Effectiveness of Lifestyle Intervention, Metformin, and Anti-Obesity Pharmacotherapy Abstract Prediabetes represents a critical window for intervention in the trajectory toward type 2 diabetes mellitus, offering family physicians an opportunity to prevent or significantly delay disease onset. With global
Expert Guide: Managing Cardiovascular-Kidney-Metabolic Syndrome in Clinical Practice
Expert Guide Managing Cardiovascular-Kidney-Metabolic Syndrome in Clinical Practice Introduction Cardiovascular kidney metabolic syndrome represents one of the most urgent and complex health challenges of the modern era. The global burden of cardiovascular disease continues to rise at an alarming pace, with prevalence increasing from approximately
Precision Endocrinology: How Genomic Testing Improves Thyroid Treatment Outcomes
Precision Endocrinology How Genomic Testing Improves Thyroid Treatment Outcomes Introduction Precision endocrinology represents a paradigm shift in the management of thyroid disorders, grounded in an expanding body of genetic and molecular evidence. Large scale genetic studies have demonstrated that approximately 57 to 71 percent
