GLP-1 Agonists for NASH Treatment: New Clinical Evidence Reveals Surprising Results Introduction Non-alcoholic fatty liver disease (NAFLD) has emerged as a major global health concern, affecting approximately one in four individuals worldwide. It is now recognized as the most common cause of
Author: Nancy Ogbonna
Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025
Hidden Signs of Subclinical Cushing’s Syndrome: New Diagnostic Criteria for 2025 Introduction Subclinical Cushing’s syndrome (SCS) presents a striking diagnostic paradox. While the classic form of Cushing’s syndrome is rare, with an estimated prevalence of approximately 1 case per 100,000 individuals, subclinical Cushing’s
The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review
The Role of Plant-Based Diets in Slowing Chronic Kidney Disease Progression: An Analytical Review Abstract Background:Chronic kidney disease (CKD) affects more than 10% of the global population and is increasingly recognized as a critical public health challenge. Its rising prevalence is largely attributed to
Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment?
Thyroid Cancer Overdiagnosis: Are We Treating What Doesn’t Need Treatment? Abstract Background and Purpose:The global incidence of thyroid cancer has risen sharply over the past three decades. Data indicate that annual incidence increased from 5.0 cases per 100,000 individuals in 1975 to 14.6 cases per
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising?
Endocrine Disruptors and Fertility: What Should Endocrinologists Be Advising? Abstract Endocrine-disrupting chemicals (EDCs) have emerged as a notable concern in reproductive health, with increasing evidence linking exposure to reduced fertility in both men and women. These compounds, which include a broad spectrum of
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete?
Giant Cell Arteritis and the Rapid Rise of Tocilizumab: Are Steroids Obsolete? Abstract Giant cell arteritis (GCA) is the most common form of primary systemic vasculitis in adults over 50 years of age and represents a major cause of morbidity, particularly when diagnosis and treatment are delayed. Traditionally, management
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures
New Frontiers in Sickle Cell Disease: CRISPR-Based Cures Abstract Sickle cell disease (SCD) remains one of the most pressing global health challenges, with an estimated 300,000 infants born annually with the disorder and millions more living with its lifelong complications. The burden of SCD is disproportionately higher in
When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis
When Blood Tests Lie: The Hidden Truth About Seronegative Rheumatoid Arthritis Introduction Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that primarily targets synovial joints, leading to progressive inflammation, cartilage destruction, and bone erosion. Traditionally, diagnosis has relied heavily on the detection of
Venetoclax-based Regimens in AML: The New Standard or a Temporary Fix?
Venetoclax-based Regimens in AML: The New Standard or a Temporary Fix? Abstract Acute myeloid leukemia (AML) remains a challenging hematologic malignancy, particularly among older adults and patients unfit for intensive chemotherapy. Over the past decade, treatment models have shifted with the advent of venetoclax, a selective BCL-2 inhibitor,
Testosterone Replacement Therapy: New Guidelines Challenge Old Beliefs
Testosterone Replacement Therapy: New Guidelines Challenge Old Beliefs Introduction Testosterone replacement therapy (TRT) usage has risen sharply over the past two decades, with rates tripling across the United States. By 2013, an estimated 2.3 million American men were receiving this treatment, reflecting both
