Postoperative Delirium and Brain Health Can the Anesthesiologist Prevent Dementia Abstract Postoperative delirium has emerged as a major concern in perioperative medicine, particularly among older adults undergoing surgical procedures. Characterized by an acute and fluctuating disturbance in attention, awareness, and cognition, postoperative delirium affects
Author: Nancy Ogbonna
CRISPR and Gene Editing in Neurodegenerative Diseases: Current Applications and Future Therapeutic Potential
CRISPR and Gene Editing in Neurodegenerative Diseases Current Applications and Future Therapeutic Potential Abstract Neurodegenerative diseases continue to pose profound challenges to modern medicine, affecting millions of individuals worldwide and contributing significantly to disability, mortality, and healthcare expenditure. Disorders such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease,
Cefepime Neurotoxicity: Underrecognized Risk or Overblown Concern?
Cefepime Neurotoxicity Underrecognized Risk or Overblown Concern Abstract Cefepime is a fourth generation cephalosporin antibiotic that is widely utilized in clinical practice for the treatment of severe and life threatening bacterial infections, including hospital acquired pneumonia, febrile neutropenia, complicated urinary tract infections, and infections caused by
LDL Targets Below 40 mg/dL: How Low Is Too Low in 2026?
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns?
mRNA Vaccines in Pregnancy: Reassurance or Lingering Concerns? Abstract This paper reviews the current body of evidence regarding the safety and effectiveness of messenger RNA COVID-19 vaccines during pregnancy and explores the broader implications for emerging mRNA vaccine platforms intended for use in pregnant populations.
The Decline of Physical Examination Skills in Internal Medicine: An Existential Threat?
The Decline of Physical Examination Skills in Internal Medicine An Existential Threat Abstract The physical examination has historically served as a central pillar of medical practice, guiding diagnostic reasoning, informing clinical decision making, and fostering meaningful physician patient relationships. For generations, proficiency in bedside examination has
The Great Vitamin D Debate: Optimal Levels, Supplementation, and Clinical Outcomes
The Great Vitamin D Debate Optimal Levels, Supplementation, and Clinical Outcomes Abstract Vitamin D deficiency is among the most common nutritional disorders globally, affecting an estimated one billion individuals across a wide range of ages, ethnicities, and geographic regions. Contributing factors include limited sunlight
Why Do Teens Vape? New Research Reveals Hidden Brain Changes
Why Do Teens Vape? New Research Reveals Hidden Brain Changes Introduction Despite increasing public awareness of the health risks associated with nicotine use, vaping remains highly prevalent among adolescents. According to 2024 data from the Centers for Disease Control and Prevention, 8.1 percent of
Preventing the Next Pandemic: Critical Insights from SARS-CoV-2 Surveillance Systems
Preventing the Next Pandemic Critical Insights from SARS-CoV-2 Surveillance Systems Introduction Preventing the next global pandemic requires a clear understanding of the profound and multifaceted impact of SARS-CoV-2, the virus responsible for COVID-19. Since its emergence, SARS-CoV-2 has infected millions of people worldwide and caused
Noninvasive Prenatal Testing (NIPT): What’s Next After Aneuploidy?
Noninvasive Prenatal Testing (NIPT) What’s Next After Aneuploidy Abstract Noninvasive prenatal testing has fundamentally reshaped prenatal screening by enabling highly accurate detection of fetal chromosomal abnormalities through analysis of cell free fetal DNA circulating in maternal blood. Since its clinical introduction, NIPT has been widely
