Resistant Starch and Short-Chain Fatty Acids: A Comprehensive Review of Physiologic Mechanisms and Clinical Relevance Comprehensive Guide Abstract Resistant starch represents a distinct category of dietary carbohydrate that escapes digestion in the small intestine and undergoes fermentation by colonic bacteria. This process generates short-chain fatty
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Coronary Artery Calcium–Guided Prevention and Microbiome-Centered Nutrition
Coronary Artery Calcium–Guided Prevention and Microbiome-Centered Nutrition: A Physician-Focused Review Integrating the Clinical Framework of William Davis, MD Quick Summary CAC is most useful when you’re on the fence. In borderline/intermediate-risk patients—or when risk markers conflict—CAC can clarify preventive intensity and improve
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility
Glucagon-Like Peptide-1 Receptor Agonists and Human Fertility: Mechanisms, Evidence, and Clinical Implications Abstract Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are well established for the treatment of type 2 diabetes mellitus and obesity. Increasingly, reports suggest a possible association between GLP-1 RA use and
Emerging and Approved Therapeutic Peptides: Mechanisms, Clinical Uses
Emerging and Approved Therapeutic Peptides: Mechanisms, Clinical Uses, Safety Profiles, and Regulatory Status Across Health Conditions Abstract Therapeutic peptides represent a rapidly growing class of pharmaceutical agents that bridge the gap between small molecule drugs and large protein therapeutics. This paper examines the
The New Frontier in Longevity Science: Senolytics and Age-Reversal Therapies
The New Frontier in Longevity Science: Senolytics and Age-Reversal Therapies Introduction Approximately 80% of adults over age 65 worldwide develop at least one chronic condition, from arthritis to dementia. Recent longevity research has identified cellular senescence as a fundamental driver of age-related decline. These
BPH Treatment Guidelines 2025: Expert-Validated Algorithm for Patient Care
BPH Treatment Guidelines 2025: Expert-Validated Algorithm for Patient Care Introduction Benign prostatic hyperplasia (BPH) treatment guidelines continue to evolve as the condition affects an overwhelming majority of aging men, with prevalence rates reaching 60% by age 60 and escalating to 80% by age
Why Medicine Feels Broken- And What Doctors Are Doing to Reclaim Their Lives
Why Medicine Feels Broken — And What Doctors Are Doing to Reclaim Their Lives Abstract The medical profession faces an unprecedented crisis marked by widespread physician burnout, administrative burden, and declining job satisfaction. This analysis examines the systemic factors contributing to the perception
Mind, Body & Immunity: 60 Psychological Insights Into How Mental Health Influences Physical Health
Mind, Body & Immunity: 60 Psychological Insights Into How Mental Health Influences Physical Health Abstract This paper examines the relationship between psychological states and physical health outcomes through an analysis of 60 evidence-based insights. The research draws from current studies in psychoneuroimmunology, behavioral
Stress, Resilience & Modern Life: 45 Psychology Facts That Help You Thrive in Chaos
Stress, Resilience & Modern Life: 45 Psychology Facts That Help You Thrive in Chaos Abstract This paper examines the psychological foundations of stress and resilience within contemporary society, addressing the challenges faced by educated professionals across diverse industries. Drawing from current research in clinical
Mental Health in the Digital Age: 50 Facts on Screen Time and Well-Being
Mental Health in the Digital Age: 50 Facts on Screen Time, Isolation, Social Media Effects, and Well-Being Abstract This paper examines the relationship between digital technology use and mental health outcomes in contemporary society. The research presents 50 evidence-based facts covering screen time
