Alcohol Consumption And The Long-Term Risk Of Mortality Overview This study aims to update a previous systematic review by conducting a comprehensive analysis of meta-analyses published from January 1, 2017, to March 8, 2021, to quantify sex-specific dose–response risk relationships between chronic alcohol consumption and disease occurrence and mortality. The systematic search
Cardiology
Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease
Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease The Study The study aimed to investigate the connection between localized vascular and retinal nerve fiber layer (RNFL) loss and an individual's genetic predisposition to both glaucoma and cardiovascular disease. Researchers used a statistical tool called polygenic risk scores (PRS) to assess
Visceral Adiposity And Heart Failure Risk
Visceral Adiposity And Heart Failure Risk Overview Obesity is a common risk factor developing for heart failure (HF). In this study, we aimed to explore the potential of the Visceral Adiposity Index (VAI) as a straightforward tool for assessing obesity and its link to HF risk, a relationship that had not been
Hydroxyurea: Pediatric Use in Sickle Cell Anemia
Hydroxyurea: Pediatric Use in Sickle Cell Anemia Overview This retrospective cohort study aimed to investigate the relationship between adherence to hydroxyurea treatment and clinical outcomes in children and adolescents with sickle cell anemia (SCA). The study utilized Medicaid data spanning from 2005 to 2012 across several U.S. states, focusing on children aged
Antithyroid Drug Therapy And Cardiovascular Morbidity
Antithyroid Drug Therapy And Cardiovascular Morbidity Overview The impact of thyroid function test (TFT) variability and its link to adverse health outcomes in antithyroid drug (ATD) therapy remains an unexplored area. This study aimed to investigate the relationship between TFT variability and cardiovascular morbidity during ATD therapy. Conducted at Tampere University Hospital,
Chronic Hyponatremia in Acute Heart Failure
Chronic Hyponatremia in Acute Heart Failure Overview This study aimed to comprehensively assess hyponatremia in patients with acute heart failure (AHF), focusing on its prevalence, associations, hospital course, and post-discharge outcomes. The research analyzed a cohort of 8,298 AHF patients from the European Society of Cardiology Heart Failure Long-Term Registry, regardless of
Maternal Migraines And Associated Pediatric Cancers
Maternal Migraines And Associated Pediatric Cancers Overview Maternal migraines are seen to be associated with unfavorable birth outcomes such as congenital malformations in babies, preterm births and infant low birth weight. It has been hypothesized that these unfavorable or adverse birth outcomes may be due to the intake of certain medications during
What to Use: Chemical or Natural Sunscreens?
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. What to Use: Chemical or Natural Sunscreens? Whether you’re going surfing or simply going on your commute to work, putting on sunscreen is a must. Sunscreens not only protects your
Cholesterol Screening To Aid In Glaucoma Detection
Cholesterol Screening To Aid In Glaucoma Detection Overview Although intraocular pressure is the primary risk factor for glaucoma, additional risk factors should also be considered. This systematic review and meta-analysis summarize the evidence of the association between cholesterol parameters (total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels) and glaucoma and
Aprocitentan in resistant hypertension
Aprocitentan in resistant hypertension Since the 1960s, modern studies of hypertension and the availability of antihypertensive drugs have significantly improved blood pressure control. However, it has reached a plateau in high-income countries in the past decade. Many patients who have uncontrolled BP despite three antihypertensive treatments at optimal dose and from