Hydroxyurea: Pediatric Use in Sickle Cell Anemia Overview This retrospective cohort study aimed to investigate the relationship between adherence to hydroxyurea treatment and clinical outcomes in children and adolescents with sickle cell anemia (SCA). The study utilized Medicaid data spanning from 2005 to 2012 across several U.S. states, focusing on children aged
Cardiology
Antithyroid Drug Therapy And Cardiovascular Morbidity
Antithyroid Drug Therapy And Cardiovascular Morbidity Overview The impact of thyroid function test (TFT) variability and its link to adverse health outcomes in antithyroid drug (ATD) therapy remains an unexplored area. This study aimed to investigate the relationship between TFT variability and cardiovascular morbidity during ATD therapy. Conducted at Tampere University Hospital,
Chronic Hyponatremia in Acute Heart Failure
Chronic Hyponatremia in Acute Heart Failure Overview This study aimed to comprehensively assess hyponatremia in patients with acute heart failure (AHF), focusing on its prevalence, associations, hospital course, and post-discharge outcomes. The research analyzed a cohort of 8,298 AHF patients from the European Society of Cardiology Heart Failure Long-Term Registry, regardless of
Maternal Migraines And Associated Pediatric Cancers
Maternal Migraines And Associated Pediatric Cancers Overview Maternal migraines are seen to be associated with unfavorable birth outcomes such as congenital malformations in babies, preterm births and infant low birth weight. It has been hypothesized that these unfavorable or adverse birth outcomes may be due to the intake of certain medications during
What to Use: Chemical or Natural Sunscreens?
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. What to Use: Chemical or Natural Sunscreens? Whether you’re going surfing or simply going on your commute to work, putting on sunscreen is a must. Sunscreens not only protects your
Cholesterol Screening To Aid In Glaucoma Detection
Cholesterol Screening To Aid In Glaucoma Detection Overview Although intraocular pressure is the primary risk factor for glaucoma, additional risk factors should also be considered. This systematic review and meta-analysis summarize the evidence of the association between cholesterol parameters (total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels) and glaucoma and
Aprocitentan in resistant hypertension
Aprocitentan in resistant hypertension Since the 1960s, modern studies of hypertension and the availability of antihypertensive drugs have significantly improved blood pressure control. However, it has reached a plateau in high-income countries in the past decade. Many patients who have uncontrolled BP despite three antihypertensive treatments at optimal dose and from
Predicting cardiovascular disease with body mass index
Predicting cardiovascular disease with Body Mass Index BMI and CVD: An Introduction Obesity, as indexed by the high body mass index (BMI), is a major risk factor for cardiovascular disease (CVD). About 60 - 80% of patients with CVD are overweight. However, there are mixed findings on the effect of decreasing BMI
Hypertension Screening for Cardiovascular Health
Hypertension Screening for Cardiovascular Health Introduction Hypertension is a contributing risk factor for cardiovascular health. In the recent European Society of Cardiology (ESC) guidelines, the main recommendation for antihypertensive treatment of patients was regarded by the future risk of cardiovascular (CV) mortality, CV disease, or total mortality. The guideline state that the
Dental Screening for Cardiovascular Disease Risk
Dental Screening for Cardiovascular Disease Risk Introduction Periodontal disease (PD) is one of the most prevalent multifactorial chronic infections, affecting 46% of US adults. Though PD occurs in the 30-40 year age range, the incidence peaks at age 38 years. Atherosclerotic cardiovascular diseases (ACVD) is caused by heredity, environment, and their interactions; conventional
