Cardiac Arrest Wearable Detection Devices And Motivated Patient Compliance Overview When an out-of-hospital cardiac arrest (OHCA) occurs, the initial step in the chain of survival is early detection. However, 75% of OHCAs go unwitnessed, which creates a significant barrier to triggering the necessary life-saving interventions. Wearable devices have the potential to act
Cardiology
Tau Accumulation And White Matter Changes Linked To Hypertension
Tau Accumulation And White Matter Changes Linked To Hypertension Overview This study explored how amyloid buildup and hypertension interact to affect tau accumulation and atrophy in the entorhinal cortex (EC), while also investigating cerebral blood flow (CBF) as a potential shared mechanism. The researchers analyzed data from two cohorts of older adults
The Fenofibrate Role In The Fight For Kidney Function Preservation
The Fenofibrate Role In The Fight For Kidney Function Preservation Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are increasingly significant global health concerns, with CKD now affecting an estimated 9.1% of the world's population—a 29.3% increase since 1990. This rise has severe implications, contributing to 1.2 million deaths annually
Alcohol Use Increases Risk Of Falling and Head Trauma In Geriatric Population
Alcohol Use Increases Risk Of Falling and Head Trauma In Geriatric Population Overview Falls are a prevalent concern among adults aged 65 and older and represent the leading cause of traumatic brain injuries in this age group. Alcohol consumption may elevate the risk of falls and exacerbate the severity of related injuries.
Vaccination Gives Protection From the Flu And Improves Heart Attack Mortality Risk
Vaccination Gives Protection From the Flu And Improves Heart Attack Mortality Risk Overview The ongoing debate about the survival benefits of influenza vaccination and the duration of its protective effects is addressed by this study, which employed a self-controlled case series (SCCS) and a matched case-control design. Utilizing data from the National
Tafamidis Reduces Mortality Rates In Cardiomyopathy Patients
Tafamidis Reduces Mortality Rates In Cardiomyopathy Patients Overview The study explored the effectiveness of tafamidis in patients with transthyretin amyloid cardiomyopathy (ATTR-CM) across varying levels of left ventricular ejection fraction (LVEF). Conducted as part of the phase 3 ATTR-ACT trial and its subsequent long-term extension (LTE) study, patients were initially randomized to
Heart Transplant Patient Confessions About Life Quality
Heart Transplant Patient Confessions About Life Quality Overview Survival rates following heart transplantation (HTx) have markedly improved over recent decades, underscoring the need to examine the long-term quality of life (QoL) for these patients. This study assessed the QoL of 75 individuals who had survived 20 to 31 years (average 24.9 years)
Selexipag Therapy Effective For Pulmonary Hypertension Patients
Selexipag Therapy Effective For Pulmonary Hypertension Patients Pulmonary arterial hypertension associated with connective tissue disease (PAH-CTD) presents a significant clinical challenge, with affected patients often experiencing worse outcomes than those with idiopathic pulmonary arterial hypertension (IPAH). Although earlier short-term studies suggested a limited response to PAH-specific therapies in PAH-CTD patients, recent
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients Overview Valoctocogene roxaparvovec is a gene therapy utilizing an adeno-associated virus serotype 5 (AAV5) vector, approved for treating severe hemophilia A (HA). The purpose of this summary is to present the safety and efficacy outcomes observed seven years post-dosing in a phase
Erythropoietin Powerful Therapy For Anemia In Pregnant Patients
Erythropoietin Powerful Therapy For Anemia In Pregnant Patients Overview Treatment options for severe, refractory iron deficiency anemia during pregnancy are quite limited. This review aimed to examine the available literature on the use of recombinant erythropoietin for treating this condition in pregnant women. A thorough search was conducted across seven databases, covering
