Overactive Bladder Therapy: Patient Desire For Implantable Tibial Nerve Stimulator Overview Third-tier treatments for overactive bladder (OAB) presently encompass intravesical Onabotulinumtoxin-A injections (BTX-A), percutaneous tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM). A recent addition to this array is the implantable tibial nerve stimulator (ITNS), offering a novel therapeutic avenue for OAB
Tag: prescription medication
Remimazolam: The Greatest New Medication In Anesthesia?
Remimazolam: The Greatest New Medication In Anesthesia? This research introduces remimazolam, a novel intravenous anesthetic that improves anesthesia quality, particularly in procedures like transcatheter aortic valve replacement (TAVR). Remimazolam offers advantages such as smooth administration, stable circulatory dynamics, and shorter half-life compared to traditional benzodiazepines. The study investigates remimazolam's potential anti-inflammatory
Wound Care: Treatment Options For Pain
Wound Care: Treatment Options For Pain Overview The management of pain involved with wound care, particularly during dressing changes, presents challenges due to the discomfort associated with these procedures. While pharmacological pain management strategies may have adverse effects and hinder wound care and healing, non-pharmacological interventions offer an alternative approach. However, the
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis
Abrocitinib In The Treatment Of Moderate to Severe Atopic Dermatitis Overview This study examined the efficacy and safety of abrocitinib, a treatment for moderate-to-severe atopic dermatitis (AD), specifically focusing on patients with allergic comorbidities. Data from phase 2b and phase 3 trials were analyzed, pooling information from patients who received abrocitinib or
Piclidenoson In The Treatment Of Plaque Psoriasis
Piclidenoson In The Treatment Of Plaque Psoriasis Overview The study focused on evaluating the effectiveness and safety of piclidenoson (CF101), an orally bioavailable agonist for the A3 adenosine receptor (A3AR), in treating moderate-to-severe plaque psoriasis. The A3AR is known to be overexpressed in the skin and peripheral blood mononuclear cells of individuals
White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients
White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients Overview In this study, the objective was to evaluate white matter microstructural changes in older breast cancer survivors 5-15 years post-chemotherapy treatment. The participants included breast cancer survivors aged 65 or older who underwent chemotherapy (C+) and those who did not (C-), along
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults
Anticholinergic Medications And Cognitive Outcomes In Autistic Adults Overview This study investigates the impact of anticholinergic (AC) medications on cognitive outcomes in autistic adults, an area that has not been extensively researched. AC medications, known for their potential to cause cognitive impairment, are commonly used for various medical and psychiatric conditions. In
Salbutamol: A Safety Meta-Analysis
Salbutamol: A Safety Meta-Analysis Overview Salbutamol, a widely used bronchospasm reliever, has been insufficiently scrutinized for potential risks. In a meta-analysis of 58 randomized controlled trials with 12,961 participants, the study unearthed a 34% incidence of total adverse events (AEs). Notably, severe AEs stood at 2%, and treatment discontinuation was 3%. Subgroup
Seizure Therapy And White Matter Changes
Seizure Therapy And White Matter Changes Functional seizures (FS) are a type of functional neurological symptom disorder that mimics epileptic seizures but lacks epileptiform changes on electroencephalography. The neuropathophysiology involves various brain systems, such as sensorimotor, emotion regulation, cognitive control, and multimodal integration. Neurobehavioral therapy (NBT) has emerged as a viable treatment
Metronidazole For Vulval Crohn’s Disease Treatment
Metronidazole For Vulval Crohn's Disease Treatment Overview Cutaneous vulval Crohn's disease (VCD), an often overlooked extra-intestinal manifestation of Crohn's disease (CD), poses diagnostic and therapeutic challenges due to its potential for significant edema, painful fissures, and lasting disfigurement of the vulval anatomy. The lack of consensus on optimal management adds to the
