Corticosteroids In Osteoarthritis Therapy: Scarce Evidence For A Superior Drug And Dose

Corticosteroids In Osteoarthritis Therapy: Scarce Evidence For A Superior Drug And Dose Overview ​​The objective of this study was to measure and compare the clinical significance of various intra-articular corticosteroids (CS) in treating osteoarthritis (OA). In October 2023, a comprehensive search was conducted using PubMed, Cochrane, and Web of Science databases, adhering to

Brilliant Use Of Probiotic Medication To Treat Psoriasis

Brilliant Use Of Probiotic Medication To Treat Psoriasis Psoriasis, a chronic inflammatory skin disease, severely affects physical and mental health, often causing severe itching. Its prevalence is increasing, especially in developed countries, and is linked to genetics, immune disorders, infections, and environmental factors. Traditional treatments include topical corticosteroids and biologics, but

Latest Research Exploring Metformin Connection To Breast Cancer

Latest Research Exploring Metformin Connection To Breast Cancer Overview This study aimed to investigate the relationship between metformin and other antidiabetic medications and the incidence of breast cancer in two large prospective cohort studies. It included 185,181 women from the Nurses' Health Study (NHS; 1994–2016) and NHSII (1995–2017). Information on type 2

Kawasaki disease: Meta Analysis Reveals A Capable Steroid Combination Therapy

Kawasaki disease: Meta Analysis Reveals A Capable Steroid Combination Therapy Overview Kawasaki disease (KD) poses significant challenges as an acute vasculitis primarily affecting the coronary arteries in children, potentially leading to fatal complications if left untreated. Corticosteroids, notably glucocorticoids, have emerged as crucial therapeutic agents in managing KD and associated cutaneous wounds.

Oral Tranexamic Acid Treatment For Blushing Rosacea Patients Enhances Skin Barrier

Oral Tranexamic Acid Treatment For Blushing Rosacea Patients Enhances Skin Barrier Overview Papulopustular rosacea (PPR) presents a persistent challenge due to its chronic nature and the substantial impact it has on facial appearance and patient well-being. Central to the pathogenesis of PPR is an impaired skin barrier, which not only exacerbates the

Statin Therapy To Smash Cardiovascular Risk In Diabetic Patients

Statin Therapy To Smash Cardiovascular Risk In Diabetic Patients Overview The study aimed to assess the impact of statin therapy on preventing cardiovascular diseases (CVDs) in patients with type 2 diabetes mellitus (T2DM), considering their baseline low-density lipoprotein cholesterol (LDL-C) levels. Researchers analyzed data from electronic medical records in Hong Kong spanning

Precision Medication Therapy Strategy In Crohn’s Disease: Financial Advantages

Precision Medication Therapy Strategy In Crohn's Disease: Financial Advantages Overview In this study, the cost-effectiveness of precision-guided dosing (PGD) of infliximab (IFX) for patients with Crohn's disease (CD) who lose response to biologics was evaluated in comparison to two other dose intensification strategies (DIS).   A hybrid model combining Markov and decision tree elements

Soaring Medication Costs: Specialty Drug Access Barriers

Soaring Medication Costs: Specialty Drug Access Barriers Overview The contemporary pharmaceutical landscape is characterized by a surge medication costs, especially for the introduction of high-cost specialty drugs, marking a notable shift in treatment paradigms. These medications often carry staggering price tags, ranging from tens to hundreds of thousands of dollars per treatment

Wound Healing In Oncology: The Acupuncture Advantage

Wound Healing In Oncology: The Acupuncture Advantage Overview In this meta-analysis, researchers aimed to evaluate the effectiveness of acupuncture in improving wound healing in patients experiencing leukopenia following chemotherapy for malignant tumors. They conducted a thorough search for randomized controlled trials and observational studies focusing on post-chemotherapy leukopenia in cancer patients. Data

Overactive Bladder Therapy: Patient Desire For Implantable Tibial Nerve Stimulator

Overactive Bladder Therapy: Patient Desire For Implantable Tibial Nerve Stimulator Overview Third-tier treatments for overactive bladder (OAB) presently encompass intravesical Onabotulinumtoxin-A injections (BTX-A), percutaneous tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM). A recent addition to this array is the implantable tibial nerve stimulator (ITNS), offering a novel therapeutic avenue for OAB

Corticosteroids In Osteoarthritis Therapy: Scarce Evidence For A Superior Drug And Dose