First Seizure Effects on Cognition in Adults

First Seizure Effects on Cognition in Adults Overview   Investigating cognitive and psychological functioning in adults after their first seizure, prior to epilepsy diagnosis and treatment, is crucial for understanding the early manifestations of neuropsychological comorbidities associated with chronic epilepsy. In this study, conducted through a telehealth-based prospective design, cognition, mood, and anxiety

White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients

White Matter Brain Changes In Post-Chemotherapy Breast Cancer Patients Overview In this study, the objective was to evaluate white matter microstructural changes in older breast cancer survivors 5-15 years post-chemotherapy treatment. The participants included breast cancer survivors aged 65 or older who underwent chemotherapy (C+) and those who did not (C-), along

Seizure Therapy And White Matter Changes

Seizure Therapy And White Matter Changes Functional seizures (FS) are a type of functional neurological symptom disorder that mimics epileptic seizures but lacks epileptiform changes on electroencephalography. The neuropathophysiology involves various brain systems, such as sensorimotor, emotion regulation, cognitive control, and multimodal integration.  Neurobehavioral therapy (NBT) has emerged as a viable treatment

Concussion Symptom Treatment Using Acoustic Stimulation

Concussion Symptom Treatment Using Acoustic Stimulation In the U.S. military, over 370,000 service members have had mild traumatic brain injuries (mTBI) or concussions since 2000, possibly more due to underreporting. While most recover within 7–30 days, about 15% face persistent postconcussive symptoms (PPCS) for at least 3 months. Despite the end

Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus

Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus Overview   In the management of mild to moderate myasthenia gravis (MG), the utilization of tacrolimus is typically reserved for cases that do not respond to glucocorticoids. This study sought to assess the potential advantages of mono-tacrolimus over mono-glucocorticoids in treating MG patients. The primary endpoint

Hydrocephalus Shunt Type: A Comparative Meta-Analysis Of Safety And Efficacy

Hydrocephalus Shunt Type: A Comparative Meta-Analysis Of Safety And Efficacy Since the inaugural hydrocephalus shunt in 1956, the ventriculoperitoneal shunt (VPS) has emerged as the primary surgical intervention for cerebrospinal fluid (CSF) diversion in North America and Europe. Despite its effectiveness, VPS entails risks such as brain hemorrhages, damage, infections, and

Music Therapy For Dementia Symptoms Treatment

Music Therapy For Dementia Symptoms Treatment Overview The study explores the impact of individualized music listening (IML) on the behavioral and psychological symptoms of dementia (BPSD), a topic previously assessed through proxy-completed questionnaires. To address methodological limitations, the researchers employed a systematic observational approach, incorporating a validated instrument, time-based sampling, and longitudinal

Antidiabetic Medications And Dementia Risk

Antidiabetic Medications And Dementia Risk Overview This umbrella review and meta-analysis aimed to assess the impact of diabetes on dementia risk and investigate the potential mitigating effects of various antidiabetic treatments. The study conducted a systematic review on diabetes and its treatment, along with a meta-analysis specifically focusing on treatment outcomes. A comprehensive

Idiopathic Parkinson’s Tremors: Treatment Options

Idiopathic Parkinson's Tremors: Treatment Options The study examines the clinical importance of tremors in idiopathic Parkinson's disease (iPD) and the difficulties encountered in their management. It underscores the diversity of iPD patients and the various symptoms they experience, notably tremors, which significantly affect their quality of life. Despite historical efforts to

Ganaxolone Treatment For Refractory Epilepsy

Ganaxolone Treatment For Refractory Epilepsy Overview In a meta-analysis conducted to evaluate the use of ganaxolone for refractory epilepsy, researchers collected data from four randomized controlled trials involving a total of 659 patients. The analysis revealed that ganaxolone significantly improved the reduction in mean seizure frequency by ≥50% when compared to a

First Seizure Effects on Cognition in Adults