Oral Insulin Breakthroughs In Development INTRODUCTION Diabetes is a chronic metabolic disorder primarily classified into two types: type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM). T1DM, an autoimmune disease often diagnosed in adolescence, is marked by the body's inability to produce insulin. In contrast, T2DM, which constitutes the majority
Tag: medication
Dental Extraction Prophylaxis Treatment With Antibiotics Is Controversial
Dental Extraction Prophylaxis Treatment With Antibiotics Is Controversial Overview This study aimed to assess the relationship between antibiotic prophylaxis and adverse outcomes following dental extractions within the Veterans Affairs Healthcare System. Researchers conducted a retrospective cohort analysis of patients who underwent tooth extractions from 2015 to 2019, focusing on antibiotic use and
Oxymetazoline Successful Therapy To Improve Droopy Eye Appearance
Oxymetazoline Successful Therapy To Improve Droopy Eye Appearance Overview Oxymetazoline hydrochloride has demonstrated effectiveness in several studies for treating acquired blepharoptosis and improving the aesthetic appearance of the upper eyelid. This study systematically reviewed existing literature on the topical use of oxymetazoline for the treatment of acquired blepharoptosis. A comprehensive review was
Antipsychotic Injectable Medications Deplete Neurotrophic Factor In Schizophrenia Patients
Antipsychotic Injectable Medications Deplete Neurotrophic Factor In Schizophrenia Patients Overview Schizophrenia (SCZ) and schizoaffective disorder (SAD) are severe psychiatric conditions influenced by both genetic and environmental factors. Serum brain-derived neurotrophic factor (BDNF) has been identified as a potential biomarker for these disorders, though its temporal changes remain unclear. This study analyzes data
The Fenofibrate Role In The Fight For Kidney Function Preservation
The Fenofibrate Role In The Fight For Kidney Function Preservation Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are increasingly significant global health concerns, with CKD now affecting an estimated 9.1% of the world's population—a 29.3% increase since 1990. This rise has severe implications, contributing to 1.2 million deaths annually
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients
Valoctocogene Roxaparvovec Gene Therapy Success Detailed For Hemophilia A Patients Overview Valoctocogene roxaparvovec is a gene therapy utilizing an adeno-associated virus serotype 5 (AAV5) vector, approved for treating severe hemophilia A (HA). The purpose of this summary is to present the safety and efficacy outcomes observed seven years post-dosing in a phase
Efgartigimod Provides Genuine Benefit For Myasthenia Gravis Disease
Efgartigimod Provides Genuine Benefit For Myasthenia Gravis Disease Overview Efgartigimod, a neonatal Fc receptor inhibitor, has recently received approval for the treatment of myasthenia gravis (MG). This retrospective cohort study systematically evaluated the short- and long-term efficacy of efgartigimod in patients with refractory MG. Sixteen patients with autoimmune acetylcholine receptor MG, who
Semaglutide Use Shows Bonus Benefit Of Osteoarthritis Risk Reduction
Semaglutide Use Shows Bonus Benefit Of Osteoarthritis Risk Reduction Overview Osteoarthritis (OA) is a widespread degenerative joint condition. While the influence of obesity on OA is well-established, the effect of semaglutide on OA remains less understood. The objective was to evaluate the effect of semaglutide on the risk of OA among patients with
Corticosteroids In Osteoarthritis Therapy: Scarce Evidence For A Superior Drug And Dose
Corticosteroids In Osteoarthritis Therapy: Scarce Evidence For A Superior Drug And Dose Overview The objective of this study was to measure and compare the clinical significance of various intra-articular corticosteroids (CS) in treating osteoarthritis (OA). In October 2023, a comprehensive search was conducted using PubMed, Cochrane, and Web of Science databases, adhering to
Intranasal Vitamin B12 Is Promising Therapy For The Geriatric Population
Intranasal Vitamin B12 Is Promising Therapy For The Geriatric Population Overview Vitamin B12 deficiency is prevalent among the elderly. Traditional treatment through intramuscular injections has notable drawbacks, prompting the exploration of safer and more convenient methods such as intranasal administration. This study evaluates the effects of two intranasal vitamin B12 dosing regimens
