Heart Failure Polygenic Risk Predictions

Heart Failure Polygenic Risk Predictions Overview This study explores the genetic associations and risk prediction capabilities of polygenic risk scores (PRSs) derived from risk factors shared with heart failure (HF) in bi-racial populations. The risk factors considered include atrial fibrillation (AF), body mass index (BMI), coronary heart disease (CHD), systolic blood pressure

Seizure Detection Algorithm Using Heart Rate Variability

Seizure Detection Algorithm Using Heart Rate Variability Overview This study aimed to validate a novel seizure detection algorithm, based on heart rate variability (HRV) and logistic regression machine learning (LRML), in a Brazilian patient cohort undergoing long-term video-electroencephalography (LTM) monitoring. The LRML algorithm had shown promise in a Danish patient cohort, and

Constipation Effect On Readmission In Heart Failure Patients

Constipation Effect On Readmission In Heart Failure Patients Constipation, a prevalent gastrointestinal disorder in Japan, affects 34.8 per 1000 individuals, rising with age and linked to factors like reduced dietary fiber and physical activity. Chronic constipation, unlike other functional gastrointestinal diseases, exhibits a significantly higher mortality risk, particularly notable in cardiovascular

N95 Mask Wearing By Dentists: An Evaluation Of Cardiovascular Effects

N95 Mask Wearing By Dentists: An Evaluation Of Cardiovascular Effects Overview Limited research exists on cardiovascular changes in dentists using N95 respirators or surgical mask-covered N95s during pediatric dental procedures. This crossover clinical trial involved 18 healthy dentists, exploring cardiovascular responses while treating pediatric patients with either an N95 respirator or a

Bariatric Surgery In Hypertrophic Cardiomyopathy Patients

Bariatric Surgery In Hypertrophic Cardiomyopathy Patients Overview Existing research has hinted at a link between obesity and increased risk of acute cardiovascular events. Bariatric surgery has been shown to mitigate this risk; however, its impact on patients with both obesity and hypertrophic cardiomyopathy (HCM) remains unclear. This study aimed to assess whether

Acute Gout And Cardiovascular Events: Exploring the Role of Inflammation

Acute Gout And Cardiovascular Events: Exploring The Role Of Inflammation Overview In this study, the association between hospital admissions due to acute gout and major adverse cardiovascular events (MACEs) was investigated using data from the Hospital Morbidity Data Collection and Death Registrations of the Western Australian Rheumatic Disease Epidemiology Registry. The aim

Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease

Retinal Nerve Fiber Wedge Defects In Glaucoma And Heart Disease The Study The study aimed to investigate the connection between localized vascular and retinal nerve fiber layer (RNFL) loss and an individual's genetic predisposition to both glaucoma and cardiovascular disease. Researchers used a statistical tool called polygenic risk scores (PRS) to assess

Cholesterol Screening To Aid In Glaucoma Detection

Cholesterol Screening To Aid In Glaucoma Detection Overview Although intraocular pressure is the primary risk factor for glaucoma, additional risk factors should also be considered. This systematic review and meta-analysis summarize the evidence of the association between cholesterol parameters (total cholesterol, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels) and glaucoma and

Aprocitentan in resistant hypertension

Aprocitentan in resistant hypertension Since the 1960s, modern studies of hypertension and the availability of antihypertensive drugs have significantly improved blood pressure control. However, it has reached a plateau in high-income countries in the past decade. Many patients who have uncontrolled BP despite three antihypertensive treatments at optimal dose and from

Heart Failure Polygenic Risk Predictions