IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Oncology
Visual Field Defects in Patients with Pituitary Tumors
Visual Field Defects in Patients with Pituitary Tumors Overview Automated perimetry is a standardized technique for assessing the visual field, commonly using the Humphrey Field Analyser (HFA) with the 24-2 or 30-2 test patterns. This study aimed to determine if the 24-2 test pattern could yield similar outcomes as the 30-2 pattern
Levothyroxine Treatment In Patients With Thyroid Cancer
Levothyroxine Treatment In Patients With Thyroid Cancer The quest to establish effective therapy for hypothyroid obese patients remains ongoing, largely due to the challenge posed by thyrotropin-stimulating hormone (TSH) levels as a dependable marker of euthyroidism compared to nonobese patients. The positive correlation between TSH levels and body mass index (BMI)
Cancer Care: Gender Bias In Decision-Making
Cancer Care: Gender Bias In Decision-Making Overview In the realm of cancer care, the integration and execution of shared decision-making within clinical practice guidelines (CPGs) and consensus statements could potentially exhibit gender-based disparities. This study aimed to meticulously analyze recommendations pertaining to shared decision-making within CPGs and consensus statements, specifically focusing on
Gynecologic Cancer Survivors: A Study Of Lifestyle Factors
Gynecologic Cancer Survivors: A Study Of Lifestyle Factors Overview Promoting positive outcomes for gynecologic cancer survivors hinges on upholding a healthy lifestyle. We scrutinized behaviors among gynecologic cancer survivors (n = 1824) and non-cancer individuals via cross-sectional analysis, using 2020 Behavioral Risk Factor Surveillance System data. Colorectal cancer screening rates were 7.9%
Non-Hodgkin Lymphoma Survivors: Secondary Malignancy Risk
Non-Hodgkin Lymphoma Survivors: Secondary Malignancy Risk The number of non-Hodgkin lymphoma (NHL) cases is rising, with an estimated 81,560 new diagnoses in the US in 2021. As survival rates improve, more NHL survivors face potential late effects, including secondary malignancies (SM) linked to treatments like chemotherapy and radiation. This research revisits
Eosinophilic Dermatosis In Hematological Malignancy (EDHM): Case Study Reports
Eosinophilic Dermatosis In Malignancy (EDHM): Case Study Reports Overview Patients with hematological malignancies may develop various skin eruptions, and one such condition is eosinophilic dermatosis of hematological malignancy (EDHM), also known as an 'insect bite-like' reaction. While cutaneous reactions are not uncommon in hematological malignancies, EDHM is a relatively rare condition that
Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness
Uterine Leiomyosarcoma: Systemic Therapy Effectiveness Overview Uterine leiomyosarcoma (uLMS) is an aggressive type of mesenchymal tumor linked to a bleak prognosis. The primary treatment for advanced uLMS is systemic chemotherapy, although the most effective regimen remains uncertain. To address this, we conducted an extensive analysis, including both meta-analysis and metaregression, aiming to
Off-label Medication Use In Oncology
Off-label Medication Use In Oncology Cancer Research and Medicinal Drugs Cancer research and innovation are highly active, resulting in the introduction of new medications into the therapeutic arsenal. However, incorporating these new drugs into clinical practice is a challenging and time-consuming process due to regulatory requirements. Before a drug can be marketed and
Monocytosis And Patient Risk Of Malignancy And Mortality
Monocytosis And Patient Risk Of Malignancy And Mortality Monocytosis is a common occurrence in primary care, but its significance is not always clear. In adults, monocytosis is defined as having a higher-than-normal count of monocytes (a type of white blood cell) in the peripheral blood, specifically above 0.8 x 10^9/L. Monocytosis