Skin Lightening: Topical Approaches To Treatment Overview The recent removal of hydroquinone from over-the-counter skin lightening products has created a demand for modern formulations that effectively address skin pigmentation issues. A successful skin lightening formulation should be non-irritating to prevent post-inflammatory hyperpigmentation, penetrate effectively to reach the epidermal/dermal junction, incorporate anti-inflammatory ingredients,
Oncology
Encapsulated Papillary Carcinoma Membrane Characteristics
Encapsulated Papillary Carcinoma Membrane Characteristics Overview This study focused on encapsulated papillary carcinoma (EPC), a type of breast carcinoma characterized by a thick fibrous capsule-like structure surrounding the tumor, often interpreted as a thickened basement membrane (BM). The primary objective was to investigate the geometric properties of the EPC capsule and determine
Ibrutinib Treatment In Waldenström Macroglobulinemia
Ibrutinib Treatment In Waldenström Macroglobulinemia Waldenström macroglobulinemia (WM) is a rare type of non-hogdkins lymphoma driven by the gene mutation MYD88L265P. Ibrutinib, the first approved treatment, is effective but can cause side effects. A study found that 27% of WM patients needed to reduce Ibrutinib doses due to side effects like
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence Overview Eyelid sebaceous gland carcinoma (SGC) is a highly malignant condition with a significant recurrence risk. This study aimed to create a predictive nomogram for SGC recurrence based on risk factors. A retrospective study involving 391 patients from one hospital (304) and grassroots hospitals (87)
Stomach Cancer: A Meta-Analysis Of Robotic Surgery Complications
Stomach Cancer: A Meta-Analysis Of Robotic Surgery Complications Gastric or stomach cancer prevalence varies significantly around the world, with higher rates in Asia, Africa, South America, and Eastern Europe. However, in the United States, stomach cancer is a growing concern due to its increased occurrence in the elderly population and its
Chemotherapy-Induced Thrombocytopenia in Nasopharyngeal Carcinoma
Chemotherapy-Induced Thrombocytopenia in Nasopharyngeal Carcinoma Overview This study aimed to investigate serious chemotherapy-induced thrombocytopenia (CIT) in nasopharyngeal carcinoma (NPC), focusing on its incidence, consequences, and predictors. The retrospective analysis of NPC patients from 2013 to 2015 revealed a 5.21% incidence of serious chemotherapy-induced thrombocytopenia. Patients experiencing severe thrombocytopenia had notably worse long-term prognoses,
Endocrine Therapy Outcomes In Senior Breast Cancer Patients
Endocrine Therapy Outcomes In Senior Breast Cancer Patients Overview This study investigated the management of early-stage, hormone receptor-positive, and human epidermal growth factor receptor 2 negative (HR+/HER2−) breast cancer in older women aged 70 to 90 years between 2010 and 2015. Specifically, it focused on patients who underwent lumpectomy and omitted radiation
Hepatocellular Carcinoma Treatment Outcomes: The Influence Of Butyrate Producers
Hepatocellular Carcinoma Treatment Outcomes: The Influence Of Butyrate Producers Overview In a retrospective multi-center study involving 747 patients with advanced hepatocellular carcinoma (HCC) treated with a combination therapy of atezolizumab and bevacizumab, the influence of butyric acid-producing enterobacteria on treatment outcomes was investigated. Previous research has established a link between the gut
Non-Invasive Breast Carcinoma Treatment Outcomes
Non-Invasive Breast Carcinoma Treatment Outcomes Overview Non-invasive breast carcinoma, distinct from invasive forms, can lead to local recurrence post-surgery, potentially progressing to invasive carcinoma and distant metastasis, impacting breast cancer prognosis. This study, involving 93 cases among 872 primary breast cancers, assessed outcomes. Surgical interventions, radiation, and endocrine therapy were common treatments.
Pilonidal Sinus Disease And Carcinoma Prevalence
Pilonidal Sinus Disease And Carcinoma Prevalence Overview This study aimed to evaluate survival and recurrence rates in pilonidal sinus disease (PSD) carcinoma. A retrospective analysis of global literature identified 140 cases published between 1900 and 2022. Survival rates were 61.7% at 3 years, 59.8% at 5 years, and 53.2% at 10 years.
