Monotherapy Or Chemotherapy Adjunct: Pembrolizumab In Advanced NSCLC Objectives To assess the effectiveness and safety of pembrolizumab monotherapy and in combination with chemotherapy in patients with advanced non–small-cell lung cancer (NSCLC). Introduction Historically, patients with advanced NSCLC have a poor prognosis despite the use of platinum-based chemotherapy drugs. The 5-year relative survival rate of
General Topics
Metastatic Melanoma and Follow-Up MRI Scans
Metastatic Melanoma and Follow-Up MRI Scans Metastatic melanoma is an aggressive tumor, which may spread to organs either by local invasion, or lymphatic or hematogenous dissemination. Central Nervous System (CNS), especially the brain, account for up to 50% of metastasis. Skin, lymph nodes, lung, and liver are other commonly involved organs,
Anlotinib with Camrelizumab in Lung Cancer Treatment
Anlotinib with Camrelizumab in Lung Cancer Treatment Background Checkpoint inhibitors (CPIs) and anti-angiogenic agents are emerging as potential novel treatment choices for advanced cancers including metastatic non-small-cell lung cancer (NSCLC). However, the combination of these two standard therapies has not been investigated in third-line or further-line treatment of patients with advanced NSCLC.
Hodgkin’s Lymphoma: A Case Study with Nystagmus and Diplopia
Hodgkin's Lymphoma: A Case Study with Nystagmus and Diplopia INTRODUCTION Paraneoplastic neurologic syndromes (PNS) are uncommon but important clinical situations caused by cancer, but not a direct result of tumor invasion. As compared to solid tumors, the chances of association of PNS with lymphomas are quite low. However, Hodgkin's and non-Hodgkin's lymphomas,
How to Plan for Unexpected Illness and Injury
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. How to Plan for Unexpected Illness and Injury When we’re young, we often think we’re invincible. The older we grow, the more we realize that it’s far from the truth
Eating to Win: Nutrition for Optimal Athletic Performance
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. Eating to Win: Nutrition for Optimal Athletic Performance Every athlete’s goal is to have the edge over their competitors. Hence, it’s essential to incorporate a comprehensive eating plan that matches
Spence Children’s Anxiety Scale Validation
Validation of Spence Children's Anxiety Scale ANXIETY IN CHILDREN In Europe, anxiety disorders are highly prevalent and impairing conditions among children and adolescents. Up to 18 - 20% of youth in the general population presenting to primary care clinics report some internalizing problem. Previous studies showed that anxiety disorders start at an early
Koolen-de Vries Case Study
Koolen-de Vries syndrome in a 63-year-old woman: a review of the adult phenotype Koolen-de Vries syndrome (KdVS): An Introduction Also known as the 17q21.31 microdeletion syndrome, Koolen-de Vries syndrome (KdVS) was first described in 2006 in individuals with intellectual disabilities and organ abnormalities. KdVS was initially described in association with recurrent microdeletion
What Electrolyte Supplements Really Do for Athletes
Patient Education This article is tailored for patients. Refer your patients to this article for them to learn more about their condition. What Electrolyte Supplements Really Do for Athletes Are sports drinks and other electrolyte supplements more hype than hope for athletes? A leading electrolyte supplement drink’s lightning bolt logo has become
Anxiety Scales in Lewy Body Disease
Anxiety Scales in Lewy Body Disease Background Anxiety disorders and symptoms are frequent in Lewy Body Disease (LBD) and many scales are available to assess its severity. Yet, there is little consensus on which scale best evaluates anxiety across LBD patients. Objective Comparing the convergent validity of commonly used anxiety scales across synuclein-based diseases. Lewy
