Are We Overtreating Early Rheumatoid Arthritis in the Biologic Era Abstract The introduction of biologic disease modifying antirheumatic drugs has fundamentally reshaped the management of rheumatoid arthritis over the past two decades. These agents, in combination with conventional synthetic therapies and treat to target strategies, have significantly
Family Practice Medicine
Biological vs Chronological Age: Are Geriatricians Ready for ‘Aging Clocks’?
Biological vs Chronological Age: Are Geriatricians Ready for ‘Aging Clocks’? Abstract The concept of biological age versus chronological age represents a fundamental shift in how healthcare providers assess aging and age-related health risks. While chronological age measures the time elapsed since birth, biological
Metformin in 2025: Still the King or Time to Step Aside?
Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron
Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron Abstract Anemia of chronic disease (ACD) represents the second most common form of anemia worldwide, affecting millions of patients with underlying inflammatory conditions. Traditionally understood as a disorder primarily involving disruption of iron metabolism, recent
Hidden Crisis: Why Sarcopenia Treatment Matters More Than You Think in 2025
Hidden Crisis: Why Sarcopenia Treatment Matters More Than You Think in 2025 Introduction Sarcopenia treatment represents a critical healthcare priority as the prevalence of this age-related muscle wasting condition reaches alarming levels. The economic burden of sarcopenia in the United States was approximately
The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy?
The Tirzepatide Revolution: Is Dual Agonism the End of Single-Pathway Therapy? Abstract The development of tirzepatide, a first in class dual glucose dependent insulinotropic polypeptide and glucagon like peptide 1 receptor agonist, represents a potentially transformative advance in the management of type 2 diabetes and obesity. By simultaneously targeting
BPH Treatment Guidelines 2025: Expert-Validated Algorithm for Patient Care
BPH Treatment Guidelines 2025: Expert-Validated Algorithm for Patient Care Introduction Benign prostatic hyperplasia (BPH) treatment guidelines continue to evolve as the condition affects an overwhelming majority of aging men, with prevalence rates reaching 60% by age 60 and escalating to 80% by age
Why Medicine Feels Broken- And What Doctors Are Doing to Reclaim Their Lives
Why Medicine Feels Broken — And What Doctors Are Doing to Reclaim Their Lives Abstract The medical profession faces an unprecedented crisis marked by widespread physician burnout, administrative burden, and declining job satisfaction. This analysis examines the systemic factors contributing to the perception
Long COVID Treatment Breakthrough- From Symptoms to Science-Backed Solutions
Direct-to-Consumer Lab Testing: Help or Hindrance for Internists?
Direct-to-Consumer Lab Testing: Help or Hindrance for Internists? Check out our extensive video library (see channel for our latest videos) Abstract Direct-to-consumer laboratory testing has become an increasingly prominent feature of modern healthcare, offering patients the ability to independently order diagnostic tests without the
