IGF-1 Levels In Pediatric Low-Grade Gliomas Overview This study investigated elevated insulin-like growth factor 1 (IGF-1) levels in children with low-grade glioma (LGG). Elevated IGF-1 levels in LGG are not well understood. The research aimed to determine the prevalence, connections with growth, body mass index (BMI), pituitary function, and tumor behavior in
Endocrinology
Visual Field Defects in Patients with Pituitary Tumors
Visual Field Defects in Patients with Pituitary Tumors Overview Automated perimetry is a standardized technique for assessing the visual field, commonly using the Humphrey Field Analyser (HFA) with the 24-2 or 30-2 test patterns. This study aimed to determine if the 24-2 test pattern could yield similar outcomes as the 30-2 pattern
Levothyroxine Treatment In Patients With Thyroid Cancer
Levothyroxine Treatment In Patients With Thyroid Cancer The quest to establish effective therapy for hypothyroid obese patients remains ongoing, largely due to the challenge posed by thyrotropin-stimulating hormone (TSH) levels as a dependable marker of euthyroidism compared to nonobese patients. The positive correlation between TSH levels and body mass index (BMI)
Ocular Surgery In Infants And Post-Op Eye Drop Risks
Ocular Surgery In Infants And Post-Op Eye Drop Risks Overview This clinical observational cohort study delves into the prevalence and risk factors associated with hypothalamus-pituitary-adrenal (HPA) axis suppression in infants subjected to glucocorticoid (GC) eye drops subsequent to ocular surgery, focusing on cataract and glaucoma procedures. The research aims to discern the
Antithyroid Drug Therapy And Cardiovascular Morbidity
Antithyroid Drug Therapy And Cardiovascular Morbidity Overview The impact of thyroid function test (TFT) variability and its link to adverse health outcomes in antithyroid drug (ATD) therapy remains an unexplored area. This study aimed to investigate the relationship between TFT variability and cardiovascular morbidity during ATD therapy. Conducted at Tampere University Hospital,
Uterine Leiomyosarcoma: A Meta-Analysis Of Systemic Therapy Effectiveness
Uterine Leiomyosarcoma: Systemic Therapy Effectiveness Overview Uterine leiomyosarcoma (uLMS) is an aggressive type of mesenchymal tumor linked to a bleak prognosis. The primary treatment for advanced uLMS is systemic chemotherapy, although the most effective regimen remains uncertain. To address this, we conducted an extensive analysis, including both meta-analysis and metaregression, aiming to
Sarcopenia And Chronic Kidney Disease
Sarcopenia And Chronic Kidney Disease Overview Sarcopenia and frailty are common conditions among people with chronic kidney disease (CKD), which may further enhance their risk of developing adverse health complications. Only a few studies have demonstrated the association between sarcopenia, frailty and chronic kidney disease in patients who are not on dialysis.
Childhood Obesity: Targeted Dietary Interventions
Childhood Obesity: Targeted Dietary Interventions Childhood obesity is a global concern, and dietary interventions have shown varying effectiveness in reducing BMI in children and adolescents. However, there is little guidance on targeted dietary approaches and energy reduction, leading to inconsistent recommendations. This excellent systematic review aimed to assess the effectiveness of
Diabetic Peripheral Neuropathy Diagnosis Using Nerve Ultrasonography
Diabetic Peripheral Neuropathy Diagnosis Using Nerve Ultrasonography Overview The conventional diagnostic modality for diabetic peripheral neuropathy is via the use of nerve conduction studies (NCS), however, this investigation does not evaluate or demonstrate the structure of the nerve. This research was aimed at investigating the use of peripheral nerve ultrasonography as a
Renal Transplant Risks With Prostate Cancer
Renal Transplant Risks With Prostate Cancer Overview Renal transplant candidates are recommended to undergo a systematic screening for prostate cancer at the time of listing. It is a growing concern that low-risk prostate cancer diagnosis may lead to reduced access to renal transplant services without any significant oncological benefit. The aim of this
