Extracorporeal Shock Wave Lithotripsy: Long-Term Effectiveness Overview The study aimed to conduct a comprehensive audit spanning seven years with a three-year follow-up at a high-volume stone center that specializes in extracorporeal shock wave lithotripsy (ESWL). The primary objectives were to assess the efficacy of ESWL in stone clearance in comparison to existing
Author: Princewill Uche Okezie
Salbutamol: A Safety Meta-Analysis
Salbutamol: A Safety Meta-Analysis Overview Salbutamol, a widely used bronchospasm reliever, has been insufficiently scrutinized for potential risks. In a meta-analysis of 58 randomized controlled trials with 12,961 participants, the study unearthed a 34% incidence of total adverse events (AEs). Notably, severe AEs stood at 2%, and treatment discontinuation was 3%. Subgroup
Parkinson’s Patients Long-Term Survival After Deep Brain Stimulation
Parkinson's Patients Long-Term Survival After Deep Brain Stimulation Overview This study investigates the long-term outcomes of patients undergoing deep brain stimulation of the subthalamic nucleus (STN-DBS) for Parkinson's disease (PD) in comparison to medical treatment (MT) alone. A cross-sectional analysis of 115 STN-DBS patients was conducted, assessing the evolution of PD symptoms
Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus
Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus Overview In the management of mild to moderate myasthenia gravis (MG), the utilization of tacrolimus is typically reserved for cases that do not respond to glucocorticoids. This study sought to assess the potential advantages of mono-tacrolimus over mono-glucocorticoids in treating MG patients. The primary endpoint
Bariatric Surgery In Hypertrophic Cardiomyopathy Patients
Bariatric Surgery In Hypertrophic Cardiomyopathy Patients Overview Existing research has hinted at a link between obesity and increased risk of acute cardiovascular events. Bariatric surgery has been shown to mitigate this risk; however, its impact on patients with both obesity and hypertrophic cardiomyopathy (HCM) remains unclear. This study aimed to assess whether
Music Therapy For Dementia Symptoms Treatment
Music Therapy For Dementia Symptoms Treatment Overview The study explores the impact of individualized music listening (IML) on the behavioral and psychological symptoms of dementia (BPSD), a topic previously assessed through proxy-completed questionnaires. To address methodological limitations, the researchers employed a systematic observational approach, incorporating a validated instrument, time-based sampling, and longitudinal
Acute Gout And Cardiovascular Events: Exploring the Role of Inflammation
Acute Gout And Cardiovascular Events: Exploring The Role Of Inflammation Overview In this study, the association between hospital admissions due to acute gout and major adverse cardiovascular events (MACEs) was investigated using data from the Hospital Morbidity Data Collection and Death Registrations of the Western Australian Rheumatic Disease Epidemiology Registry. The aim
Ocrelizumab Effectiveness In Multiple Sclerosis
Ocrelizumab Effectiveness In Multiple Sclerosis Overview Throughout its clinical development program, ocrelizumab has consistently demonstrated efficacy in enhancing clinical outcomes for multiple sclerosis, encompassing annualized relapse rates and confirmed disability progression. Despite these positive findings, the translation of this efficacy into real-world clinical practice remained uncertain. This study aimed to systematically compile
Pancreatitis Risk In Patients Taking Antipsychotic Medications
Pancreatitis Risk In Patients Taking Antipsychotic Medications Overview This extensive nationwide study, spanning from 2006 to 2019, investigated the potential link between antipsychotic drug use and acute pancreatitis risk. Analyzing data from 52,006 cases and 518,081 controls, the study initially suggested an increased risk associated with both first-generation and second-generation antipsychotic drugs,
Lithium Effects On Renal Function In Geriatric Patients
Lithium Effects On Renal Function In Geriatric Patients Overview The practice of augmenting antidepressant therapy with lithium, known as Lithium Augmentation (LA), is considered a primary treatment option for individuals suffering from Treatment-Resistant Depression (TRD). However, in the case of geriatric patients, this approach is notably underutilized due to concerns surrounding potential
