Psoriasis Risk In Children With High BMI

Psoriasis Risk In Children With High BMI Overview This study aimed to investigate the potential association between childhood body mass index (BMI) and the risk of psoriasis. Using publicly available summary statistics from genome-wide association studies (GWAS) that focused on childhood BMI in individuals of European descent (n=39,620), the researchers conducted a

Traumatic Scalp Defects: Case Studies And Treatment Approaches

Traumatic Scalp Defects: Case Studies And Treatment Approaches Overview The management of traumatic scalp defects presenting with exposed calvaria devoid of pericranium is a formidable clinical challenge. This case series details the successful treatment of such cases through a combination of low-temperature plasma (LTP) and negative pressure wound therapy (NPWT). In a

Perforator Flaps For Patellar Defects

Perforator Flaps For Patellar Defects Overview This study explores the use of pedicled fascio-cutaneous perforator flaps, specifically the descending genicular artery perforator (DGAP) flap, for reconstructing complex peripatellar defects. While free flaps and pedicled muscle flaps are more commonly employed for this purpose, the DGAP flap is presented as a viable and

Blue Light Therapy For Melasma Patients

Blue Light Therapy For Melasma Patients Melasma, a common skin pigmentation condition, presents as distinctive brown spots on the face, notably affecting individuals with darker skin tones. Although the exact causes remain elusive, factors such as solar radiation, genetics, and hormonal fluctuations are believed to play pivotal roles. Solar radiation, including

Skin Lightening: Topical Approaches To Treatment

Skin Lightening: Topical Approaches To Treatment Overview The recent removal of hydroquinone from over-the-counter skin lightening products has created a demand for modern formulations that effectively address skin pigmentation issues. A successful skin lightening formulation should be non-irritating to prevent post-inflammatory hyperpigmentation, penetrate effectively to reach the epidermal/dermal junction, incorporate anti-inflammatory ingredients,

Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis

Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis Overview In a Phase III trial, a water-soluble ciclopirox nail hydrolacquer was evaluated for treating toenail fungal infection. Its enhanced penetration delivered higher ciclopirox concentration to the nail compared to existing lacquers. The study compared the hydrolacquer, its base formulation (vehicle), and an active control over

Chronic Spontaneous Urticaria: Studying Age-Specific Therapies

Chronic Spontaneous Urticaria: Studying Age-Specific Therapies Overview   Chronic spontaneous urticaria (CSU) presents differently in pediatric and adult populations. A retrospective analysis of 751 CSU patients (162 pediatrics and 589 adults) revealed shorter disease duration and lower angioedema rates in pediatric cases. Adults showed higher prevalence of anti-thyroid peroxidase positivity, elevated CRP, eosinopenia,

Eosinophilic Dermatosis In Hematological Malignancy (EDHM): Case Study Reports

Eosinophilic Dermatosis In Malignancy (EDHM): Case Study Reports Overview Patients with hematological malignancies may develop various skin eruptions, and one such condition is eosinophilic dermatosis of hematological malignancy (EDHM), also known as an 'insect bite-like' reaction. While cutaneous reactions are not uncommon in hematological malignancies, EDHM is a relatively rare condition that

Melanoma Diagnosis Without Biopsy

Melanoma Diagnosis Without Biopsy Overview Alternatives to photographic surveillance in the diagnosis of melanoma are increasingly used in dermatology practice. Traditional surveillance is done in place of photographic surveillance in the diagnosis of melanoma. This retrospective study featured melanomas which were diagnosed by three different dermatologists who have had private practice of over

Psoriasis Risk In Children With High BMI