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  • Lactulose: Acute Hepatic encephalopathy or portosystemic encephalopathy (PSE): Adults: Oral: 20-30 g (30-45 ml) every 1-2 hours to induce rapid laxation. Adjust dosage daily to produce 2-3 soft stools. Doses of 30-45 ml may be given hourly to cause rapid laxation, then reduce to recommended dose. Usual daily dose: 60-100 g (90-150 mL) daily. Rectal administration: 200 g (300 ml) diluted with 700 ml of H20 or NS – administer rectally via rectal balloon catheter and retain 30-60 minutes every 4-6 hours

 

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Common LAB Values  Renal Dosing