Alphabetical Listing of individual drugs

a b c d e f g h i j k l m
n o p q r s t u v w x y z

a

ASA 325mg + butalbital 50mg + caffeine 40mg Fiorinal ®
Ancef ® Cefazolin
Abacavir 300mg + lamivudine 150mg + zidovudine 300mg Trizivir ®
Abacavir 600mg + lamivudine 300mg Epzicom ®
Abacavir  (ziagen ®)
Abaloparatide Tymlos™
Abciximab (reopro ®) 
Abreva ® Docosanol 
Acamprosate  (campral ® )
Acarbose(precose ®)
Acarbose(precose ®) 
Accolate ® Zafirlukast
Accupril ® Quinapril
Accutane ® Isotretinoin
Ace inhibitors & diuretics
Aceon ® Perindopril 
Acetazolamide  (diamox ® )
Acetic acid + propylene glycol Vosol otic ®
Acetylcysteine  (mucomyst ®,  cetylev™ )
Achromycin ® Tetracycline 
Aciphex ® Rabeprazole
Aciphex ® Rabeprazole sodium
Acitretin - soriatane ® 
Aclidinium bromide - tudorza™ pressair™
Actifed (triprolidine 2.5mg + psuedoephedrine 60mg) 
Actigall ® Ursodiol 
Actinex ® Masoprocol  
Actonel ® Risedronate
Actos ® Pioglitazone
Acular ® Ketorolac
Acyclovir ( zovirax ® ) 
Acyclovir (zovirax ®)
Acyclovir  ( zovirax ®)
Adalimumab - humira®
Adapalene (differin ®)
Additional info
Adefovir  (hepsera ®)
Adempas® ( riociguat)
Adenosine (adenocard ®) 
Adequate intakes (ai)
Advair ® - fluticasone + salmeterol
Advicor ®  (lovastatin +niacin sr) 
Aerospan™ Flunisolide
Afrin ® Oxymetazoline 
Aggrastat ® Tirofiban
Aggrenox ® (dipyridamole/asa)
Alamast ® Pemirolast
Albendazole
Albuterol (proventil ®)
Alcaftadine - lastacaft ®
Aldactazide ® Spironolactone and hctz 
Aldactone ® Spironolactone 
Aldactone ® Spironolactone 
Aldara ® Imiquimod
Aldomet Methyldopa
Alefacept -  amevive ® 
Alendronate (fosamax ®)
Alendronate (fosamax ®) 
Alferon n Interferon alfa-n3
Alfuzosin (uroxatral ®)
Alfuzosin (uroxatral ® )
Alirocumab injection - praluent ®
Alirocumab injection - praluent ®-  
Aliskiren (tekturna®)
Alitretinoin  (panretin ® )
Allegra Fexofenadine
Allegra d
Allopurinol (zyloprim ®) 
Almond oil 
Almotriptan  (axert ®) 
Alocril ® Nedocromil
Alogliptin -nesina® 
Aloh and magnesium trisilicate ( gaviscon®)
Alomide ® Lodoxamide tromethamine
Alosetron (lotronex®)
Alprazolam (xanax ®)
Altace ® Ramipril 
Alteplase  (activase ®, t-pa)
Alum irrigation  
Aluminum hydroxide ( alternagel®)
Aluminum hydroxide  -  alternagel ®,  alu-cap ®
Alunbrig™ (brigatinib) tablets 
Alupent ® Metaproterenol
Alvimopan - entereg® capsule
Amantadine (symmetrel ®) 
Amaryl ® Glimepiride
Ambien ® Zolpidem 
Amerge ® Naratriptan 
Amidate ® Etomidate 
Amikacin  (amikin®) 
Amiloride and hctz  (moduretic ®)
Amiloride  (midamor ® )
Aminophylline
Amiodarone (cordarone ®) 
Amitiza ™ Lubiprostone 
Amlodipine (norvasc®) 
Amoxicillin/ clavulanate (augmentin ®)
Amoxicillin 
Amphetamine er orally disintegrating tablets -adzenys xr-odt 
Amphetamine suspension - dyanavel xr ™ 
Ampho b lipid (albecet ®)
Amphoterecin-b
Ampicillin/ sulbactam (unasyn ®) 
Ampicillin 
Amprenavir (agenerase ® )
Anagrelide (agrylin ®)
Ancobon ® Flucytosine
Androderm® (testosterone transdermal system)
Androgel® (testosterone gel) 1%
Androgel®  (testosterone gel) 1.62%
Angiomax ® Bivalirudin
Angiotensin-ii receptor antagonists & diuretics
Anidulafungin - eraxis ™
Anoro™ ellipta™ (umeclidinium and vilanterol inhalation powder)
Ansaid ® Flurbiprofen 
Antabuse ® Disulfiram 
Anthralin  -  drithocreme ® 
Anti-inhibitor coagulant complex  feiba® nf
Anticholinergics
Antizol ® Fomepizole
Anturane ® Sulfinpyrazone
Anusol hc (pramoxine + hc) 
Anusol suppository 
Anusol, itch-x, proctofoam, tronolane Pramoxine 1%
Anzemet ® Dolasetron
Apap 325mg + butalbital 50mg + caffeine 40mg Fioricet ®
Apixaban - eliquis®
Aprepitant (emend®)  
Apresoline ® Hydralazine
Aptivus ® Tipranavir
Aralen ® Chloroquine 
Aranesp ® Darbepoietin alfa
Aredia ® Pamidronate
Arformoterol tartrate - brovana®
Argatroban  
Aricept ® Donepezil
Aripiprazole (abilify ®) 
Arixtra ® Fondaparinux
Artane ® Trihexyphenidyl
Arthricare®, zostrix ® Capsaicin 
Arthrotec (diclofenac/ misoprostol)
Asa 325mg + butalbital 50mg + caffeine 40mg Fiorinal ®
Asacol ® , pentasa Mesalamine 
Asacol ®, pentasa ® Mesalamine
Asenapine - saphris®
Asmanex ® Mometasone furoate 
Atacand ® Candesartan
Atarax, vistaril Hydroxyzine 
Atazanavir (reyataz ® )
Atazanavir and cobicistat Evotaz™
Atenolol (tenormin ® )
Ativan ® Lorazepam
Atorvastatin (lipitor ®) 
Atovaquone (mepron ®)
Atracurium (tracrium ® ) 
Atripla™  (efavirenz, emtricitabine, and tenofovir) 
Atromid-s ® Clofibrate
Atropine
Atropine (isopto atropine)
Atrovent nasal ® Ipratropium bromide
Atrovent ® Ipratropium
Auralgan ® (benzocaine + antipyrine)
Avanafil (stendra™)
Avandamet® (rosiglitazone + metformin)
Avandamet® (rosiglitazone + metformin) 
Avandamet® (rosiglitazone + metformin)  
Avandia ® Rosiglitazone
Avapro ® Irbesartan
Aveed® (testosterone undecanoate) injection 
Avelox ® Moxifloxacin 
Avelumab Bavencio ®
Avodart ® Dutasteride
Avonex Interferon beta-1a
Avonex ® , rebif ® Interferon beta-1a 
Avycaz ™ (ceftazidime and avibactam)
Axid ® Nizatidine 
Axiron® (testosterone) topical solution
Azelaic acid (azelex ®)
Azelastine (optivar ®)
Azelastine hydrochloride and fluticasone propionate nasal spray - dymista™
Azelastine  (astelin ® )
Azilsartan medoxomil - (edarbi ®)
Azithromycin  (zithromax ®)  
Azmacort ® Triamcinolone 
Azt 300mg+150 mg lamivudine Combivir ®
Aztreonam (azactam ®)
Aztreonam - azactam ®
Azulfadine ® Sulfasalazine  
Azulfidine ® Sulfasalazine
ibs

Other agents studied for the treatment of IBS

IBS – Loperamide,  Antidepressants, Serotonergic agents, PEG laxatives

Loperamide and its role in the treatment of IBS:

Key points based on the findings from the American College of Gastroenterology:3

  • Insufficient evidence to recommend loperamide for use in IBS based on the poor quality of evidence from available clinical trials.

Findings from the American Gastroenterological Association regarding Antisoasmodics:7

  • Very limited data available regarding the treatment of IBS-D with loperamide.
  • There is a large body of ‘indirect’ evidence to support use in reducing stool frequency and based on the low cost and minimal adverse effects can be viewed as a useful adjunct.
  • Statement:  use loperamide (over no drug treatment) in patients with IBS-D. (Conditional recommendation; Very low-quality evidence)

Use of antidepressants in IBS:

Key points based on the findings from the American College of Gastroenterology:3

  • Anxiety and depression are frequent comorbidities among IBS patients.
  • TCAs and selective serotonin reuptake inhibitors are effective in relieving symptoms of IBS –>  Recommendation: weak. Quality of evidence: high.
  • Majority of trials did not differentiate between the type of IBS treated.
  •  Incidence of adverse events was significantly higher among those taking antidepressants as compared with placebo.
  • Summary statement: Available evidence does not permit guidance on patient selection for antidepressant therapy.

Findings from the American Gastroenterological Association:7

  • Available evidence (low quality)  showed that TCA therapy resulted in a modest improvement in global relief and abdominal pain.
  • Represent a low-cost treatment option and should be used with caution in patients at risk for prolongation of the QT interval.
  • Final statements: 
    • May use tricyclic antidepressants (over no drug treatment) in patients with IBS. (Conditional recommendation; Low-quality evidence).
    • No evidence to support the use of selective serotonin reuptake inhibitors for patients with IBS.


Use of PEG laxatives in IBS:

Findings from the American College of Gastroenterology and the American Gastroenterological Association regarding PEG laxatives:3,7

  • Very low quality of available evidence.
  • AGC:  no available evidence to support PEG use in controlling symptoms of IBS.
  • AGA: Large body of indirect evidence of efficacy in treating constipation —> PEG laxatives may be useful in patients with IBS-C (adjunct). Also few reported side effects and cost is low.
    Supports use of laxatives over no drug treatment.

Serotonergic agents in IBS:   Serotonin plays a critical role in gastrointestinal secretion, motility, and sensation while the serotonin subtype 3 (5-HT 3 ) receptors have been shown to play an important role in visceral pain.  5-HT 3 antagonists decrease pain from the gut and slow intestinal transit. Other receptor subtypes also impact the gastrointestinal tract.

Findings from the American College of Gastroenterology and the American Gastroenterological Association regarding PEG laxatives:3,7

  • Only one agent is recommended – 5-HT 3 antagonist (Alosetron) and it is restricted to women with severe diarrhea-predominant
    IBS. Alosetron can only be prescribed within a carefully monitored program because of the concerns regarding adverse events.

>Prosecretory agents (Linaclotide, Lubiprostone)

References

  1. Lovell RM , Ford AC . Global prevalence of, and risk factors for, irritable bowel syndrome: a meta-analysis . Clin Gastroenterol Hepatol 2012; 10 : 712 – 21 .
  2. Quigley EM , Abdel-Hamid H , Barbara G et al. A global perspective on irritable bowel syndrome: a consensus statement of the World Gastroenterology Organisation Summit Task Force on Irritable Bowel Syndrome . J Clin Gastroenterol 2012 ; 46 : 356 – 66 .
  3. Ford AC, et al.   American College of Gastroenterology monograph on the management of irritable bowel syndrome and chronic idiopathic constipation Am J Gastroenterol 2014 109 Suppl 1 S2-S26. PubMed.
  4. Chang, L., Lembo, A., and Sultan, S. American Gastroenterological Association technical review on the pharmacological management of irritable bowel syndrome. Gastroenterology. 2014; 147: 1149-1172.
  5. Simren M,  Palsson OS,  Whitehead WE. Update on Rome IV Criteria for Colorectal Disorders: Implications for Clinical Practice.  Curr Gastroenterol Rep. 2017; 19(4): 15.  Published online 2017 Apr 3. doi: 10.1007/s11894-017-0554-0 PMCID: PMC5378729
  6. Drossman DA. Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features and Rome IV. Gastroenterology. 2016;150:1262-1279.
  7. American Gastroenterological Association Institute Guideline on the Pharmacological Management of Irritable Bowel Syndrome. Accessed: July 2017. Available at:
    http://www.gastro.org/guidelines/pharmacological-management-of-ibs
  8. Zuckerman MJ. The role of fiber in the treatment of irritable bowel syndrome: therapeutic recommendations. J Clin Gastroenterol. 2006 Feb;40(2):104-8.
  9. LINZESS(R) package insert.  Allergan USA, Inc. Ironwood Pharmaceuticals, Inc. Irvine, CA 92612 Cambridge, MA, 02142.  Revised: 1/2017. Accessed: July 2017.
  10. Amitiza® (lubiprostone) package insert.  Takeda Pharmaceuticals America, Inc. Deerfield, IL 60015.  Revised: 9/2016.  Accessed: July 2017.