Salbutamol: A Safety Meta-Analysis Overview Salbutamol, a widely used bronchospasm reliever, has been insufficiently scrutinized for potential risks. In a meta-analysis of 58 randomized controlled trials with 12,961 participants, the study unearthed a 34% incidence of total adverse events (AEs). Notably, severe AEs stood at 2%, and treatment discontinuation was 3%. Subgroup
Pulmonology
N95 Mask Wearing By Dentists: An Evaluation Of Cardiovascular Effects
N95 Mask Wearing By Dentists: An Evaluation Of Cardiovascular Effects Overview Limited research exists on cardiovascular changes in dentists using N95 respirators or surgical mask-covered N95s during pediatric dental procedures. This crossover clinical trial involved 18 healthy dentists, exploring cardiovascular responses while treating pediatric patients with either an N95 respirator or a
Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus
Myasthenia Gravis Therapeutic Benefits Of Monotherapy With Tacrolimus Overview In the management of mild to moderate myasthenia gravis (MG), the utilization of tacrolimus is typically reserved for cases that do not respond to glucocorticoids. This study sought to assess the potential advantages of mono-tacrolimus over mono-glucocorticoids in treating MG patients. The primary endpoint
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients Overview In this retrospective cohort study utilizing IQVIA PharMetrics Plus claims data, the effectiveness of mepolizumab, a humanized anti-interleukin 5 monoclonal antibody, was explored in a real-world setting for U.S. patients with severe asthma and comorbid chronic rhinosinusitis (CRS) with or without sinus
