Off-label Medication Use In Oncology Cancer Research and Medicinal Drugs Cancer research and innovation are highly active, resulting in the introduction of new medications into the therapeutic arsenal. However, incorporating these new drugs into clinical practice is a challenging and time-consuming process due to regulatory requirements. Before a drug can be marketed and
Oncology
Monocytosis And Patient Risk Of Malignancy And Mortality
Monocytosis And Patient Risk Of Malignancy And Mortality Monocytosis is a common occurrence in primary care, but its significance is not always clear. In adults, monocytosis is defined as having a higher-than-normal count of monocytes (a type of white blood cell) in the peripheral blood, specifically above 0.8 x 10^9/L. Monocytosis
Bedside Pediatric Early Warning System: A Validation Study
Bedside Pediatric Early Warning System: A Validation Study Overview Conducted in an 80-bed pediatric oncology specialty hospital in the Netherlands, this research was initiated to evaluate the predictive utility of the adapted Bedside Pediatric Early Warning System (BedsidePEWS) score. This study aimed to explore the correlation of this score with unanticipated transfers
Massage Therapy For Oncology Patient Pain
Massage Therapy For Oncology Patient Pain Overview This study aimed to investigate the impact of massage therapy (MT) as a nonpharmacologic approach for addressing various symptoms experienced by children, adolescents, and young adults with hematologic and/or oncologic conditions. The researchers focused on two patient groups: those with sickle cell disease (SCD) and
Eyelid Rhabdomyosarcoma Survival In Children’s Oncology
Eyelid Rhabdomyosarcoma Survival In Children's Oncology Overview Survival outcomes in Orbital Rhabdomyosarcoma (ORMS) typically show excellent results, especially in low-risk cases (stage 1, group I-III, embryonal RMS). However, long-term follow-up data on low-risk ORMS and less common subgroups treated in recent Children's Oncology Group (COG) trials were previously unreported. To fill this
Acute Myeloid Leukemia And Diverse Patient Survival Outcomes
Acute Myeloid Leukemia And Diverse Patient Survival Outcomes Background Cancer remains a prominent global health concern, accounting for a significant number of cases and fatalities worldwide in 2020, with projections indicating further increases in both incidence and mortality rates, particularly in the United States. Hematologic malignancies (HMs) constitute a substantial subset of
Sarcopenia And Chronic Kidney Disease
Sarcopenia And Chronic Kidney Disease Overview Sarcopenia and frailty are common conditions among people with chronic kidney disease (CKD), which may further enhance their risk of developing adverse health complications. Only a few studies have demonstrated the association between sarcopenia, frailty and chronic kidney disease in patients who are not on dialysis.
IBD: A Link To Cancer And Infection
IBD: A Link To Cancer And Infection Individuals diagnosed with inflammatory bowel disease (IBD) face higher susceptibility to malignancy and infection when compared to the general population. The primary objective of this study was to identify and describe risk factors associated with malignancy or serious infection in patients with IBD, with a
Renal Transplant Risks With Prostate Cancer
Renal Transplant Risks With Prostate Cancer Overview Renal transplant candidates are recommended to undergo a systematic screening for prostate cancer at the time of listing. It is a growing concern that low-risk prostate cancer diagnosis may lead to reduced access to renal transplant services without any significant oncological benefit. The aim of this
Urothelial Carcinoma – Ureteral and Renal Pelvic Tumors
Urothelial Carcinoma - Ureteral and Renal Pelvic Tumors Overview Ureteropelvic and renal pelvic carcinoma have similar origins, however, variations in genetic and clinical parameters makes them two distinct conditions. The single-center data obtained for the molecular subtypes and characteristics of the two muscle-invasive tumors were validated using clinical data from the Surveillance,
