Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis Overview In a Phase III trial, a water-soluble ciclopirox nail hydrolacquer was evaluated for treating toenail fungal infection. Its enhanced penetration delivered higher ciclopirox concentration to the nail compared to existing lacquers. The study compared the hydrolacquer, its base formulation (vehicle), and an active control over
Author: Princewill Uche Okezie
Chronic Spontaneous Urticaria: Studying Age-Specific Therapies
Chronic Spontaneous Urticaria: Studying Age-Specific Therapies Overview Chronic spontaneous urticaria (CSU) presents differently in pediatric and adult populations. A retrospective analysis of 751 CSU patients (162 pediatrics and 589 adults) revealed shorter disease duration and lower angioedema rates in pediatric cases. Adults showed higher prevalence of anti-thyroid peroxidase positivity, elevated CRP, eosinopenia,
Ocular Surgery In Infants And Post-Op Eye Drop Risks
Ocular Surgery In Infants And Post-Op Eye Drop Risks Overview This clinical observational cohort study delves into the prevalence and risk factors associated with hypothalamus-pituitary-adrenal (HPA) axis suppression in infants subjected to glucocorticoid (GC) eye drops subsequent to ocular surgery, focusing on cataract and glaucoma procedures. The research aims to discern the
Gynecologic Cancer Survivors: A Study Of Lifestyle Factors
Gynecologic Cancer Survivors: A Study Of Lifestyle Factors Overview Promoting positive outcomes for gynecologic cancer survivors hinges on upholding a healthy lifestyle. We scrutinized behaviors among gynecologic cancer survivors (n = 1824) and non-cancer individuals via cross-sectional analysis, using 2020 Behavioral Risk Factor Surveillance System data. Colorectal cancer screening rates were 7.9%
Bedside Pediatric Early Warning System: A Validation Study
Bedside Pediatric Early Warning System: A Validation Study Overview Conducted in an 80-bed pediatric oncology specialty hospital in the Netherlands, this research was initiated to evaluate the predictive utility of the adapted Bedside Pediatric Early Warning System (BedsidePEWS) score. This study aimed to explore the correlation of this score with unanticipated transfers
Supragastric Belching And Acid Reflux Severity
Supragastric Belching And Acid Reflux Severity SGB, known as supragastric belching, is a behavioral disorder where individuals rapidly inhale and expel air. It is commonly observed in those experiencing symptoms resembling acid reflux, as well as in individuals with excessive belching. Studies in the past have indicated a higher prevalence of
