Golimumab Compliance In Long-Term Arthritis Treatment STUDY BACKGROUND Biological and targeted synthetic disease-modifying antirheumatic drugs (bDMARDs and tsDMARDs) are the cornerstones in treating inflammatory arthritides such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (SpA). Tumor necrosis factor-alpha (TNFα) inhibitors, including adalimumab, infliximab and golimumab are the most commonly prescribed
Author: Nivil Gopi
Survival trends: pancreatic cancer in the USA
survival trends: pancreatic cancer in the USA STUDY BACKGROUND Pancreatic cancer (PC) is a devastating malignancy with a 5-year survival rate of 10%. Despite accounting for only 3% of all new cancer diagnoses, it is the third leading cause of cancer-related deaths in the US. Surgical resection is the only potentially curative
nusinersen therapy for pediatric spinal muscular atrophy
nusinersen therapy for pediatric spinal muscular atrophy Study Background Spinal muscular atrophy (SMA) is an inherited motor neuron disease caused by the degeneration of anterior horn cells of the spinal cord and brainstem. SMA primarily affects babies and young children and has an incidence of 1:10,000. It is caused by a homozygous
pediatric liver transplantation: a new biological abdominal wall
pediatric liver transplantation: a new biological abdominal wall Study Background Liver transplantation (LT) is the only definitive treatment for children with advanced liver disease. Pediatric liver transplantation has evolved significantly over the past few decades, with excellent short-term and long-term survival rates. However, graft matching challenges, especially size-matched donors, remain. Also, in
Influenza surveillance: A Review of Data Sources
Influenza surveillance: A Review of Data Sources Objective In recent years, influenza surveillance systems have started to include alternative data sources such as hospital emergency department data, school absenteeism reports, pharmaceutical sales, website access and health/medical advice calls. This scoping review aims to map the published papers on the use of non-traditional/alternative
macular edema therapy using dexamethasone nanoparticle suspension
macular edema therapy using dexamethasone nanoparticle suspension PURPOSE To determine the effectiveness and safety of a new topical nanoparticle dexamethasone ophthalmic suspension OCS-01 (Oculis SA, Lausanne, Switzerland) in the treatment of diabetic macular edema (DME). STUDY BACKGROUND Diabetic macular edema (DME) is the main cause of visual impairment in patients with diabetic retinopathy (DR).
Satiation And Satiety: An Overview And Clinical Calculator
Satiation And Satiety: An Overview And Clinical Calculator Satiation and satiety are often confused and used interchangeably, though both are physiologically and behaviorally different sensations. Satiation describes the series of processes that cause one to stop eating. Governed by hormones and gastric stretch receptors, satiation occurs during an eating episode and
Hearing Screening After Chemotherapy: A Study On Childhood Cancer Survivors
Hearing Screening After Chemotherapy: A Study On Childhood Cancer Survivors The Study Background The survival rates of children with cancer have increased steadily since the mid-1970s, from 58% to 85% in developed countries. However, these improvements are tainted by immediate and late effects of treatment. Geenen et al. and Oeffinger et al.
cancer diagnosis and mental health
cancer diagnosis and mental health Introduction Cancer diagnosis and treatment evokes despair in patients. Compared with healthy individuals, cancer patients are at a high risk of psychological problems. It has been estimated that approximately one-third of cancer patients in the world are affected by mental disorders, with depression and anxiety being the
Prostate Cancer: A New Biopsy Risk Calculator using MRI
Prostate Cancer: A New Biopsy Risk Calculator using MRI Study Background In men, prostate cancer (PCa) is the most commonly diagnosed malignancy in over 50% of countries. Despite this statistic, a large number of prostate cancer cases are not clinically significant and are unlikely to lead to problems if left untreated. Differentiating
