Metronidazole For Vulval Crohn's Disease Treatment Overview Cutaneous vulval Crohn's disease (VCD), an often overlooked extra-intestinal manifestation of Crohn's disease (CD), poses diagnostic and therapeutic challenges due to its potential for significant edema, painful fissures, and lasting disfigurement of the vulval anatomy. The lack of consensus on optimal management adds to the
Tag: dermatology
Rosacea Therapy Using Botulinum Toxin
Rosacea Therapy Using Botulinum Toxin Rosacea is a long-term inflammatory disease that affects the face primarily, with symptoms such as recurrent flushing, persistent erythema, and potential papular and pustular lesions, impacting patients' physical and mental health. Traditional treatments are often insufficient, leading to recurrent attacks and necessitating maintenance therapy. Botulinum toxin
Dermatitis And Allergies To Cosmetic Ingredients
Dermatitis And Allergies To Cosmetic Ingredients Overview In the realm of hair cosmetics, a plethora of products harbor various potent contact allergens, including additives such as preservatives. This concern is particularly pronounced among individuals involved in hairdressing, who frequently manifest hand dermatitis. Furthermore, clients and self-users, hereafter referred to as 'consumers,' may
Azelaic Acid Treatment For Rosacea and Melasma
Azelaic Acid Treatment For Rosacea and Melasma Overview This study evaluated the effectiveness and safety of topical azelaic acid (AA) for various dermatological conditions, including acne vulgaris, rosacea, hyperpigmentation/melasma, and skin aging. The researchers conducted a systematic review of randomized controlled trials (RCTs) with a minimum treatment duration of 6 weeks, searching
Secukinumab Therapy In Psoriasis
Secukinumab Therapy In Psoriasis Overview Psoriasis is a chronic skin condition characterized by immune-mediated inflammation, significantly affecting patients' quality of life. Secukinumab, an interleukin 17A inhibitor, has been employed as a systemic treatment for psoriasis. However, its long-term retention rates in a real-world setting in Japan have not been comprehensively studied. In
Squamous Cell Carcinoma And Immunosuppression Risks
Squamous Cell Carcinoma And Immunosuppression Risks Overview This study aimed to compare the clinical characteristics and outcomes of cutaneous squamous cell carcinoma (cSCC) in immunosuppressed and immunocompetent patients. The retrospective analysis included 935 cSCC cases, with 19.5% of the patients being immunosuppressed. The study revealed several notable findings: Immunosuppressed patients with
Necrotizing Fasciitis Treatment And Bacterial Isolates Mortality Risk
Necrotizing Fasciitis Treatment And Bacterial Isolates Mortality Risk Necrotizing fasciitis, although rare, is a highly concerning and progressive medical condition. Its rarity doesn't diminish its potential to become life-threatening due to the systemic toxicity it can unleash on the body. This condition is primarily characterized by a fast-spreading infection within the
Acellular Dermal Matrix (ADM) For Burn and Trauma Wounds
Acellular Dermal Matrix (ADM) For Burn and Trauma Wounds In full-thickness skin defects, involving the epidermis, dermis, and subcutaneous tissue, skin grafting is a common method for repair. Traditional grafting involves cutting the patient's own skin for transplantation, with variations like ultra-thin split-thickness, medium-thickness, and full-thickness grafts depending on skin thickness
Psoriasis Risk In Children With High BMI
Psoriasis Risk In Children With High BMI Overview This study aimed to investigate the potential association between childhood body mass index (BMI) and the risk of psoriasis. Using publicly available summary statistics from genome-wide association studies (GWAS) that focused on childhood BMI in individuals of European descent (n=39,620), the researchers conducted a
Traumatic Scalp Defects: Case Studies And Treatment Approaches
Traumatic Scalp Defects: Case Studies And Treatment Approaches Overview The management of traumatic scalp defects presenting with exposed calvaria devoid of pericranium is a formidable clinical challenge. This case series details the successful treatment of such cases through a combination of low-temperature plasma (LTP) and negative pressure wound therapy (NPWT). In a
