Surgical Success Of Crohn's Disease Interventions Overview Recent evidence questions the existing approach of reserving surgery for ileocaecal Crohn's disease (CD) patients only when complications arise. This study aimed to compare the short-term outcomes of patients who underwent primary ileocaecal resection for either an inflammatory phenotype (luminal disease, earlier in the disease
Tag: Crohn’s disease
(CCD) Cutaneous Crohn’s Disease Manifestations In The Pediatric Population
(CCD) Cutaneous Crohn's Disease Manifestations In The Pediatric Population Overview Cutaneous Crohn's disease (CCD), also referred to as metastatic Crohn's disease, is a rare but often underrecognized condition characterized by granulomatous inflammation affecting the skin. This study investigates the demographic, clinical, histological features, and treatment outcomes of 89 pediatric cases of CCD,
Methotrexate Accumulation In Patient Guts: Target Intestinal Mucosa Variation By Disease State
Methotrexate Accumulation In Patient Guts: Target Intestinal Mucosa Variation By Disease State Overview This study investigates the accumulation of intracellular methotrexate polyglutamates (MTX-PGs) in different cell types to identify a more accurate biomarker for methotrexate (MTX) therapy in Crohn’s disease (CD) patients. MTX-PG3 concentrations in red blood cells (RBCs) are known to
Colitis Risk Increase In Inflammatory Eye Disease Patients
Colitis Risk Increase In Inflammatory Eye Disease Patients Overview Microscopic colitis (MC) is an inflammatory condition affecting the colon, but its association with inflammatory eye diseases remains unclear. This study aimed to determine if inflammatory eye diseases, specifically iridocyclitis and episcleritis, are risk factors for developing MC. Using the ESPRESSO database, which includes
Precision Medication Therapy Strategy In Crohn’s Disease: Financial Advantages
Precision Medication Therapy Strategy In Crohn's Disease: Financial Advantages Overview In this study, the cost-effectiveness of precision-guided dosing (PGD) of infliximab (IFX) for patients with Crohn's disease (CD) who lose response to biologics was evaluated in comparison to two other dose intensification strategies (DIS). A hybrid model combining Markov and decision tree elements
Fistula Presence As A Cancer Risk Factor In Crohn’s Disease
Fistula Presence As A Cancer Risk Factor In Crohn's Disease Overview In this retrospective cohort study, the researchers aimed to delve into the cancer risk among patients with Crohn's disease (CD) based on the presence or absence of perianal fistulas (PF). The study spanned from January 1, 2013, to December 31, 2014,
Metronidazole For Vulval Crohn’s Disease Treatment
Metronidazole For Vulval Crohn's Disease Treatment Overview Cutaneous vulval Crohn's disease (VCD), an often overlooked extra-intestinal manifestation of Crohn's disease (CD), poses diagnostic and therapeutic challenges due to its potential for significant edema, painful fissures, and lasting disfigurement of the vulval anatomy. The lack of consensus on optimal management adds to the
