pediatric leukemia patients utilizing levofloxacin STUDY BACKGROUND Bacterial infection-related morbidity and mortality are high in children treated for acute myeloid leukemia (AML) and relapsed acute lymphoblastic leukemia (rALL). Bacteremia not only contributes to mortality but also prolongs hospitalization, delays chemotherapy, decreases the quality of life, and requires the administration of costly and
Tag: cancer
Breast Cancer And An Analysis of Cardiovascular Events
Breast Cancer And An Analysis of Cardiovascular Events Breast cancer is considered one of the most common cancers in the world. In 2020, there are 7.8 million women diagnosed with breast cancer globally. It also has resulted in more than 700,000 deaths based on the data from WHO. Unlike other cancers
Monotherapy Or Chemotherapy Adjunct: Pembrolizumab In Advanced NSCLC
Monotherapy Or Chemotherapy Adjunct: Pembrolizumab In Advanced NSCLC Objectives To assess the effectiveness and safety of pembrolizumab monotherapy and in combination with chemotherapy in patients with advanced non–small-cell lung cancer (NSCLC). Introduction Historically, patients with advanced NSCLC have a poor prognosis despite the use of platinum-based chemotherapy drugs. The 5-year relative survival rate of
Advanced Gastric Cancer: Prognosis With Nivolumab Monotherapy
Advanced Gastric Cancer: Prognosis With Nivolumab Monotherapy Overview Later-line treatments for advanced gastric cancer have always been debated. Although chemotherapy is the recommended option. For the last decade, immune checkpoint inhibitors have been used for the treatment of various malignancies. Trials have also been performed for gastric cancer. In this study, a
Sinonasal B‐cell lymphomas: A Cohort Study on Progression and Recurrence
Sinonasal B‐cell lymphomas: A Cohort Study on Progression and Recurrence STUDY BACKGROUND Sinonasal lymphoma is a rare malignancy of rhinologic origin affecting the sinonasal region and surrounding structures. It is a type of non-Hodgkin lymphoma (NHL) comprising around 1.5% of all lymphomas and usually involves males aged between 40 and 70 years.
Diffuse-Type Tenosynovial Giant Cell Tumors: Treatments and Progression
Diffuse-Type Tenosynovial Giant Cell Tumors: Treatments and Progression Tenosynovial giant cell tumors (TGCT) - An Introduction Tenosynovial giant cell tumors (TGCT) are rare, locally invasive lesions of synovial origin that involve joints, tendon sheaths, and bursae. TGCT may be intra- or extra-articular and is classified by growth pattern and clinical presentation as
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report Overview A male patient, 52 years of age, underwent pneumonectomy of the left lung. He was previously diagnosed with primary spindle cell carcinoma (pT4aN1M0, stage III B) with programmed death-ligand 1 expression (tumor proportion score ≥95%) and without epidermal growth factor
DNA Methylation Profiling in Sarcoma Classification
Breast Tomosynthesis Simulator for Virtual Clinical Trials
Breast Tomosynthesis Simulator for Virtual Clinical Trials Summary The use of computer models and simulation in predicting the clinical performance of x-ray imaging devices in silico and generating synthetic patient images for training and testing of machine learning algorithms is widely accepted today. In this study, the researchers presented a detailed description of
Renal Cell Carcinoma- Prognosis via Albumin Levels
Renal Cell Carcinoma- Prognosis via Albumin Levels Metastatic renal cell carcinoma (mRCC) - An Introduction Renal cell carcinoma (RCC) constitutes approximately 90% of all urologic malignancies. Approximately 30% of patients with RCC present with metastatic disease, and amongst those with localized disease, a substantial proportion will recur. Before 2005, immunotherapy with interleukin-2
