MF-BIOLOGY, MANAGEMENT, AND CASE REPORT OF OCULAR MANIFESTATION Myelofibrosis is an uncommon myeloproliferative neoplasm, a type of blood cancer where excess red blood cells, white blood cells, or platelets are produced in the bone marrow. The rarity of this abnormality has many medical professionals struggling to understand its genetic underpinnings. This
Oncology
Malignancy in Myelofibrosis Patients Receiving Ruxolitinib Therapy
A Restrospective Study of Secondary Malignancies in Myelofibrosis Patients Receiving Ruxolitinib Therapy Myelofibrosis (MF) is a chronic, rare, and often fatal type of blood cancer characterized by a progressive replacement of bone marrow with fibrous scar tissue. This type of myeloproliferative neoplasm (MPN) leads to progressive spleen enlargement, systemic symptoms such
Study on the Ocular involvement in metastatic and systemic malignancies
Ocular Involvement of Systemic Malignancies Systemic malignancies affecting the eye often involve the choroid or the orbital area of the eye, leading to different ocular manifestations. Ocular malignancies are relatively rare compared to malignancies of other parts of the human body. The American Cancer Society estimates there will be about 3,300 new eye cancer
Genetic Mutations for Predicting Pancreatic Ductal Adenocarcinoma Susceptibility
Genetic Mutations for Predicting Pancreatic Ductal Adenocarcinoma Susceptibility Pancreatic ductal adenocarcinoma (PDAC) is the deadliest malignancy representing about 90% of all pancreatic cancers. PDAC progresses asymptomatically until death and is refractory to most treatment methods. Surgery is the most effective treatment. Nevertheless, it is well known that only 15-20% of PDAC
Exploring Gene Profiles in Small Bowel Adenocarcinoma
Exploring Gene Profiles in Small Bowel Adenocarcinoma Small bowel adenocarcinoma (SBA) is one of the rarest tumors found in patients. In fact, SBA only represents about 1-3% of all gastrointestinal malignancies. Due to its rarity, genomic analyses and prognostic biomarkers are limited. About 55-82% of small bowel adenocarcinomas can be found in
3D MRI FOR NON-INVASIVE OCULAR PROTON THERAPY
3D MRI in Non-Invasive Proton Therapy Treatment Planning of Uveal Melanomas Uveal melanoma (UM) is a rare subset of melanoma, but is the most common primary intraocular tumor in adults. In 85% of cases, melanocytes in the choroid are affected. UM can occasionally arise from the ciliary body or iris. With
Oncology-Specific Opioid Risk Calculator in Cancer Survivors
Oncology-Specific Opioid Risk Calculator in Cancer Survivors Despite the great progress made in terms of diagnosis and treatment, cancer is still a dreaded diagnosis. This devastating disease has a sweeping reach. The International Agency for Research on Cancer (IARC) figures for global cancer burden estimates were 19.3 million new cases and
Quality of Life in Adolescent Cancer Survivors
Sexual Dysfunction in Prostate Cancer Treatments: Survey Results
Study Results: The Effects of Sexual Dysfunction in Prostate Cancer Patients Prostate cancer is the most common cancer in males, with more than 57,000 new cases each year. It accounts for around 26% of all male cancer cases. About one in six individuals with prostate cancer has advanced disease progression. Treatment of
3-Day Surprise Question To Predict Survival Rates in Advanced Cancer Patients
3-Day Surprise Question To Predict Survival Rates in Advanced Cancer Patients Predicting survival rates in cancer patients with grave severity is crucial for both the patient, family, and doctors. Knowing this can help everyone adjust to the treatment that will be offered. If the unfortunate news is given, this can also
