Biological vs Chronological Age: Are Geriatricians Ready for ‘Aging Clocks’?

Biological vs Chronological Age: Are Geriatricians Ready for ‘Aging Clocks’?   Abstract The concept of biological age versus chronological age represents a fundamental shift in how healthcare providers assess aging and age-related health risks. While chronological age measures the time elapsed since birth, biological

Bite Therapy: CAR-T vs T-Cell Engagers – Which Saves More B-ALL Patients?

Bite Therapy: CAR-T vs T-Cell Engagers – Which Saves More B-ALL Patients?   Introduction Bite therapy and CAR-T cell treatments have revolutionized the management of B-cell acute lymphoblastic leukemia (B-ALL), achieving remarkable remission rates. Second-generation CD19-targeted chimeric antigen receptor T cells achieve dramatic remission

Metformin in 2025: Still the King or Time to Step Aside?

Metformin in 2025: Still the King or Time to Step Aside?   Abstract Metformin has reigned as the first-line therapeutic option for type 2 diabetes mellitus for over six decades, earning its moniker as the “king” of anti-diabetic medications. As we advance through 2025, the diabetes

Epigenetics and Brain Plasticity: Can We Rewrite the Neurological Code?

Epigenetics and Brain Plasticity: Can We Rewrite the Neurological Code?   Introduction More than half of children are estimated to experience at least one form of early-life stress, contributing to 30–40% of all mood, drug, and psychiatric disorders. Neural plasticity, a remarkable characteristic of

Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron

Anemia of Chronic Disease: Unravelling New Pathways Beyond Iron   Abstract Anemia of chronic disease (ACD) represents the second most common form of anemia worldwide, affecting millions of patients with underlying inflammatory conditions. Traditionally understood as a disorder primarily involving disruption of iron metabolism, recent

Hidden Crisis: Why Sarcopenia Treatment Matters More Than You Think in 2025

Hidden Crisis: Why Sarcopenia Treatment Matters More Than You Think in 2025   Introduction Sarcopenia treatment represents a critical healthcare priority as the prevalence of this age-related muscle wasting condition reaches alarming levels. The economic burden of sarcopenia in the United States was approximately

AI Risk Scores vs HEART Score: Which Better Predicts Chest Pain Outcomes?

AI Risk Scores vs HEART Score: Which Better Predicts Chest Pain Outcomes?   Introduction In the United States, AI risk scores vs HEART score chest pain assessment represents a critical frontier in emergency medicine. Approximately 10 million patients present to emergency departments annually with

Climate Change and Children’s Health: Preparing Pediatricians for New Frontiers

Climate Change and Children’s Health: Preparing Pediatricians for New Frontiers Abstract Climate change poses serious threats to children’s health worldwide. This paper examines how environmental changes affect pediatric health outcomes and explores strategies for preparing healthcare professionals to address these challenges. By

Factor 11a Inhibitors vs DOACs: The New Standard in Anticoagulation Therapy?

Factor 11a Inhibitors vs DOACs: The New Standard in Anticoagulation Therapy? Introduction Venous thromboembolism (VTE) affects nearly 900,000 people annually in the United States, with an estimated 60,000-100,000 individuals dying from related complications. Factor 11a inhibitors represent a promising new frontier in anticoagulation

Controversies in Antiphospholipid Syndrome: DOACs vs. Warfarin

Controversies in Antiphospholipid Syndrome: DOACs vs. Warfarin  Check out our extensive video library (see channel for our latest videos) Abstract Antiphospholipid syndrome (APS) represents a complex autoimmune disorder characterized by thrombotic events and pregnancy complications in patients with persistent antiphospholipid antibodies. The traditional anticoagulant

Biological vs Chronological Age: Are Geriatricians Ready for ‘Aging Clocks’?