Spitz Lesions: Clinical Outcomes Overview The management of Spitz-type lesions in clinical practice has been a subject of debate due to the limited information available on their long-term clinical outcomes. Some medical centers opt for a conservative and observational approach, while others recommend further surgery and extended follow-up. The objective of this
Author: Princewill Uche Okezie
Biologic Therapy Tapering In Inflammatory Arthritis
Biologic Therapy Tapering In Inflammatory Arthritis Overview The aim of this study was to identify predictors of successful biologic tapering in patients with inflammatory arthritis, using baseline characteristics from the BIODOPT trial. The trial included adult patients with rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis who had been on a stable biologic
Rheumatoid Arthritis: Monitoring Disease With Neutrophil-To-Monocyte Ratio
Rheumatoid Arthritis: Monitoring Disease With Neutrophil-To-Monocyte Ratio Overview A recent case-control study conducted in Ibb City, Republic of Yemen, focused on identifying effective hematological markers for monitoring disease activity in patients with chronic rheumatoid arthritis (RA). This autoimmune disease is characterized by chronic inflammation. The study explored three novel inflammatory markers: neutrophil-monocyte
Bipolar Disorder And The Impact Of Insulin Sensitivity
Bipolar Disorder And The Impact Of Insulin Sensitivity Overview This study investigated the impact of insulin resistance (IR) and insulin sensitivity on various brain parameters in individuals with bipolar disorder (BD). Bipolar disorder is associated with structural and functional brain changes, and BD patients have an increased risk of developing insulin resistance,
PPE And Related Skin Reactions
PPE And Related Skin Reactions Overview Healthcare workers, who played a vital role during the pandemic, faced various challenges related to the use of personal protective equipment (PPE), resulting in skin issues. This study aimed to identify and understand these skin problems experienced by nurses working in intensive care units within a
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence
Eyelid Carcinoma (SGC): A Tool To Predict Recurrence Overview Eyelid sebaceous gland carcinoma (SGC) is a highly malignant condition with a significant recurrence risk. This study aimed to create a predictive nomogram for SGC recurrence based on risk factors. A retrospective study involving 391 patients from one hospital (304) and grassroots hospitals (87)
Cognitive Behavioral Therapy In Patients With Insomnia And Chronic Fatigue
Cognitive Behavioral Therapy In Patients With Insomnia And Chronic Fatigue Overview This study delves into the relationship between insomnia, chronic fatigue, and the response to cognitive behavioral therapy for insomnia (CBT-I). The research, a secondary analysis of data from a community-based randomized controlled trial, encompassed 1717 participants with self-reported insomnia. The primary
Non-Invasive Breast Carcinoma Treatment Outcomes
Non-Invasive Breast Carcinoma Treatment Outcomes Overview Non-invasive breast carcinoma, distinct from invasive forms, can lead to local recurrence post-surgery, potentially progressing to invasive carcinoma and distant metastasis, impacting breast cancer prognosis. This study, involving 93 cases among 872 primary breast cancers, assessed outcomes. Surgical interventions, radiation, and endocrine therapy were common treatments.
Pilonidal Sinus Disease And Carcinoma Prevalence
Pilonidal Sinus Disease And Carcinoma Prevalence Overview This study aimed to evaluate survival and recurrence rates in pilonidal sinus disease (PSD) carcinoma. A retrospective analysis of global literature identified 140 cases published between 1900 and 2022. Survival rates were 61.7% at 3 years, 59.8% at 5 years, and 53.2% at 10 years.
Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis
Ciclopirox Hydrolacquer Therapy For Adult Onychomycosis Overview In a Phase III trial, a water-soluble ciclopirox nail hydrolacquer was evaluated for treating toenail fungal infection. Its enhanced penetration delivered higher ciclopirox concentration to the nail compared to existing lacquers. The study compared the hydrolacquer, its base formulation (vehicle), and an active control over
