Filanesib combination therapy in multiple myeloma Overview of the Study Filanesib is a kinesin spindle protein inhibitor that’s recently proposed as a cancer treatment for multiple myeloma. In this study of the first dose-escalation phase, the researchers tried to understand the maximum tolerated dose of two schedules of filanesib, bortezomib, and dexamethasone
Author: Armela Escalona
Breast Cancer And An Analysis of Cardiovascular Events
Breast Cancer And An Analysis of Cardiovascular Events Breast cancer is considered one of the most common cancers in the world. In 2020, there are 7.8 million women diagnosed with breast cancer globally. It also has resulted in more than 700,000 deaths based on the data from WHO. Unlike other cancers
Advanced Gastric Cancer: Prognosis With Nivolumab Monotherapy
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Platinum-Resistant Recurrent Ovarian Cancer Treatment +/- Bevacizumab
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Isatuximab Treatment in Refractory T-Acute Lymphoblastic Leukemia
Isatuximab Treatment in Refractory T-Acute Lymphoblastic Leukemia The difficulty of making an accurate prognosis of acute T- cell lymphoblastic leukemia (T- ALL) and T- cell lymphoblastic lymphoma (T- LBL) in seniors and patients with relapsed illness has always been an issue in the medical field. Since there is no specified standard
Ocular Melanoma and Treatment with Metformin
Ocular Melanoma and Treatment with Metformin Metformin Activity Metformin is one of the most common medications for patients with type 2 diabetes mellitus. It is an antihyperglycemic agent that activates the adenosine monophosphate-activated kinase (AMPK). Through this, a person’s cellular ATP levels are restored. The activation of AMPK by metformin suggests that
Gastric Neuroendocrine Neoplasms
Gastric Neuroendocrine Neoplasms Overview Gastric neuroendocrine neoplasms are rare lesions found in the stomach. They grow slowly and are often divided into four types based on their clinical characteristics. Type I lesions are found in the stomach and are linked with autoimmune chronic atrophic gastritis. Type II lesions are often caused by
Sebaceous Carcinoma Treatment Outcomes: A Multicenter Study
Sebaceous Carcinoma Treatment Outcomes Sebaceous carcinoma (SC) is a rare tumor found in the sebaceous glands. The sebaceous gland is the gland that lubricates our skin. Although it can develop anywhere on the body, sebaceous carcinomas are often found on eyelids. It’s responsible for 0.7% of all cutaneous malignancies. From 2000
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report Overview A male patient, 52 years of age, underwent pneumonectomy of the left lung. He was previously diagnosed with primary spindle cell carcinoma (pT4aN1M0, stage III B) with programmed death-ligand 1 expression (tumor proportion score ≥95%) and without epidermal growth factor
DNA Methylation Profiling in Sarcoma Classification
