Diffuse-Type Tenosynovial Giant Cell Tumors: Treatments and Progression Tenosynovial giant cell tumors (TGCT) - An Introduction Tenosynovial giant cell tumors (TGCT) are rare, locally invasive lesions of synovial origin that involve joints, tendon sheaths, and bursae. TGCT may be intra- or extra-articular and is classified by growth pattern and clinical presentation as
Oncology
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report
Lung Spindle Cell Carcinoma Responsive to Pembrolizumab: A Rare Case Report Overview A male patient, 52 years of age, underwent pneumonectomy of the left lung. He was previously diagnosed with primary spindle cell carcinoma (pT4aN1M0, stage III B) with programmed death-ligand 1 expression (tumor proportion score ≥95%) and without epidermal growth factor
DNA Methylation Profiling in Sarcoma Classification
Breast Tomosynthesis Simulator for Virtual Clinical Trials
Breast Tomosynthesis Simulator for Virtual Clinical Trials Summary The use of computer models and simulation in predicting the clinical performance of x-ray imaging devices in silico and generating synthetic patient images for training and testing of machine learning algorithms is widely accepted today. In this study, the researchers presented a detailed description of
Renal Cell Carcinoma- Prognosis via Albumin Levels
Renal Cell Carcinoma- Prognosis via Albumin Levels Metastatic renal cell carcinoma (mRCC) - An Introduction Renal cell carcinoma (RCC) constitutes approximately 90% of all urologic malignancies. Approximately 30% of patients with RCC present with metastatic disease, and amongst those with localized disease, a substantial proportion will recur. Before 2005, immunotherapy with interleukin-2
Diagnostic Error Causing Cases of Cytopenia
Diagnostic Error Causing Cases of Cytopenia Summary Many psychotropic drugs are known to cause cytopenia after increasing dosage or during the beginning of treatment. Cytopenia can also be caused by other conditions such as leukemia. These two case reports report on cases of cytopenia which happened during adjustment of psychotropic mediations in
Hodgkin’s Lymphoma: A Case Study with Nystagmus and Diplopia
Hodgkin's Lymphoma: A Case Study with Nystagmus and Diplopia INTRODUCTION Paraneoplastic neurologic syndromes (PNS) are uncommon but important clinical situations caused by cancer, but not a direct result of tumor invasion. As compared to solid tumors, the chances of association of PNS with lymphomas are quite low. However, Hodgkin's and non-Hodgkin's lymphomas,
Brugada Syndrome Treated with Lenalidomide: A Case Study
Can low-dose Rd treatment be safe for patients with multiple myeloma and Brugada syndrome? How can this treatment affect a patient’s survival and quality of life? What is Multiple Myeloma? Multiple myeloma (MM) is a type of cancer that can infect plasma cells, the cells which help you fight infections by creating
Inoperable locally advanced non-small cell lung cancer: Survival rates of Endostar, CCRT
Inoperable locally advanced non-small cell lung cancer: Survival rates of Endostar, CCRT Inoperable locally advanced non-small cell lung cancer (NSCLC): An Introduction Accounting for approximately 80% of lung cancers, non-small cell lung cancer (NSCLC) is the most common subtype. Most NSCLC patients are diagnosed at an advanced stage with a mere 15-20%
Thymoma Case Report: Entire-Tumor Calcification
Thymoma Case Report: Entire-Tumor Calcification Background Thymoma is a type of anterior mediastinal tumor that is quite common. It represents around 50% of anterior mediastinal masses and around 20-30% of all types of mediastinal tumors. Thymomas are hard to distinguish between invasive or encapsulated types. Thymomas often affects patients in their middle ages.