Methotrexate Accumulation In Patient Guts: Target Intestinal Mucosa Variation By Disease State Overview This study investigates the accumulation of intracellular methotrexate polyglutamates (MTX-PGs) in different cell types to identify a more accurate biomarker for methotrexate (MTX) therapy in Crohn’s disease (CD) patients. MTX-PG3 concentrations in red blood cells (RBCs) are known to
Tag: Inflammatory diseases
Silica Dust: Does It Ignite Inflammation In The Gut And Eye
Silica Dust: Does It Ignite Inflammation In The Gut And Eye Ulcerative colitis (UC) is a chronic inflammatory ailment of the colon. It is considered a part of the inflammatory bowel disease (IBD) category. It causes inflammation and ulcers in the colon's lining, usually starting in the rectum and spreading upward.
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients
Mepolizumab Effectiveness In Asthma, Rhinosinusitis, and Sinus Surgery Patients Overview In this retrospective cohort study utilizing IQVIA PharMetrics Plus claims data, the effectiveness of mepolizumab, a humanized anti-interleukin 5 monoclonal antibody, was explored in a real-world setting for U.S. patients with severe asthma and comorbid chronic rhinosinusitis (CRS) with or without sinus
