Gram-negative, spiral (characteristic spiral/corkscrew appearance), motile and microaerophilic.
Campylobacter jejuni: main cause of bacterial foodborne disease in many developed countries.
Usual routes of transmission are fecal-oral, ingestion of contaminated food or water, and the eating of raw meat.
Symptoms: inflammatory, sometimes bloody, diarrhea, or dysentery syndrome.
Important considerations: The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions. Generally, the most common agents/regimens are listed first. Listed dosages may need to be adjusted for renal dysfunction.
Campylobacter fetus (Non-jejuni infections): Infections are usually self-limited and antibiotics are rarely needed unless symptoms persist for more than 7-10 days.
Limited to gastrointestinal tract / mild-moderate cases:
Erythromycin 250-500mg orally four times daily x 7 days.