Helicobacter pylori

Background:

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Other   (Gram Negative Bacilli)  
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>Aeromonas species:
     1] Aeromonas hydrophila
     2] Aeromonas veronii
     3] Aeromonas shubertii
>Bartonella species:
     1] Bartonella bacilliformis
     2] Bartonella henselae (organism responsible for cat scratch disease)
     3] Bartonella Quintana
     4] Other
>Campylobacter:
     1] Campylobacter fetus
     2] Campylobacter jejuni
>Capnocytophaga species:
     1] Capnocytophaga canimorsus
     2] Capnocytophaga ochracea
>Francisella tularensis
>Helicobacter pylori led
>Legionella species: ( L. pneumophila)
>Plesiomonas shigelloides
>Vibrio species:
     1] Vibrio cholera
     2] Vibrio parahaemolyticus
     3] Vibrio damsela
     4] Other

Helicobacter pylori:  

  • Gram-negative, microaerophilic bacterium found in the stomach. 
  • Linked to cases of chronic gastritis and gastric ulcers. 
  • It is also linked to the development of duodenal ulcers and stomach cancer.
  • Over 80 percent of individuals infected with the bacterium are asymptomatic.

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Therapy:

Important considerations:  The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions.   Generally, the most common agents/regimens are listed first.

  1. No allergies:  Standard PPI* (all equivalent)  PLUS clarithromycin 500 mg twice daily PLUS amoxicillin 1000 mg orally twice daily for 10 to14 days.
  2. PCN allergy:  Standard PPI* (all equivalent)  PLUS clarithromycin 500 mg twice daily PLUS metronidazole 500 mg twice daily for 10 to14 days.
  3. PCN allergy or failed one of the above regimens (quadruple therapy):   Standard PPI* (all equivalent)  PLUS  Bismuth subsalicylate 525 mg four times daily  PLUS  metronidazole 250 mg four times daily PLUS  tetracycline 500 mg four times daily for 10-14 days

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user’s use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. Read the disclaimer