Chronic Spontaneous Urticaria: Studying Age-Specific Therapies Overview Chronic spontaneous urticaria (CSU) presents differently in pediatric and adult populations. A retrospective analysis of 751 CSU patients (162 pediatrics and 589 adults) revealed shorter disease duration and lower angioedema rates in pediatric cases. Adults showed higher prevalence of anti-thyroid peroxidase positivity, elevated CRP, eosinopenia,