Overactive Bladder Therapy: Patient Desire For Implantable Tibial Nerve Stimulator Overview Third-tier treatments for overactive bladder (OAB) presently encompass intravesical Onabotulinumtoxin-A injections (BTX-A), percutaneous tibial nerve stimulation (PTNS), and sacral neuromodulation (SNM). A recent addition to this array is the implantable tibial nerve stimulator (ITNS), offering a novel therapeutic avenue for OAB