Involvement of Ocular Surface in Graft‐Versus‐Host Disease: A Review

Involvement of Ocular Surface in Graft-Versus-Host Disease: A Review Hematopoietic stem cell transplantation (HSCT) is a promising curative therapy for hematologic malignancies and other disorders of blood and bone marrow. Historically, HSCT was referred to as bone marrow transplantation (BMT) because bone marrow was the sole source of transplanted hematopoietic stem

Using Ultrasound to Analyze Malignant and Benign Orbital Space-Occupying Lesions

Using Ultrasound to Analyze Malignant and Benign Orbital Space-Occupying Lesions Most orbital space-occupying lesions come from tissues in the orbital space or metastasize from other system tumors. The bulk of clinical manifestations of these lesions such as diplopia, protrusion, and loss of vision are often nonspecific, so imaging technology is crucial

Risk Factors for Ocular Metastases in Invasive Ductal Carcinoma

Risk Factors for Ocular Metastases in Invasive Ductal Carcinoma Invasive ductal carcinoma (IDC), also known as infiltrating ductal carcinoma, is the most common type of breast cancer, accounting for about 72% of all cases. IDC can occur at any age, but many people are over the age of 55 at the

Myelofibrosis – Biology, Management, and Case Report of Ocular Manifestation

MF-BIOLOGY, MANAGEMENT, AND CASE REPORT OF OCULAR MANIFESTATION Myelofibrosis is an uncommon myeloproliferative neoplasm, a type of blood cancer where excess red blood cells, white blood cells, or platelets are produced in the bone marrow.  The rarity of this abnormality has many medical professionals struggling to understand its genetic underpinnings. This

Study on the Ocular involvement in metastatic and systemic malignancies

Ocular Involvement of Systemic Malignancies Systemic malignancies affecting the eye often involve the choroid or the orbital area of the eye, leading to different ocular manifestations. Ocular malignancies are relatively rare compared to malignancies of other parts of the human body. The American Cancer Society estimates there will be about 3,300 new eye cancer

Using Nanofiber Antibiotic Sutures Prevent Ophthalmic Infections

Using Nanofiber Antibiotic Sutures to Prevent Ophthalmic Infections Sutures are medical devices applied on the site of injury or surgery. Sutures prevent infection, minimize scarring, and fasten recovery. As of today, the only drug-eluting sutures available for antibacterial application in most surgeries are coated with >triclosan. It’s known that putting drugs

3D MRI FOR NON-INVASIVE OCULAR PROTON THERAPY

3D MRI in Non-Invasive Proton Therapy Treatment Planning of Uveal Melanomas Uveal melanoma (UM) is a rare subset of melanoma, but is the most common primary intraocular tumor in adults. In 85% of cases, melanocytes in the choroid are affected. UM can occasionally arise from the ciliary body or iris. With

Meta-Analysis to Determine Optimal Therapy Strategies in Macular Degeneration

Meta-Analysis Results of Clinical Trial Aimed at Determining Optimal Therapeutic Strategies for anti-VEGF Therapy in nAMD Background of this Study Neovascular age-related macular degeneration (nAMD) affects as many as 196 million people worldwide, and is a major cause of severe vision problems including blindness. Despite its prevalence, disagreements about the treatment options

Tool for evaluating real world evidence in treatment of retinal disease

Tool for Evaluating RWE in the Treatment of Retinal Disease   Randomized clinical trials have long been held as the gold standard for evidence based medical practices. However, there is a growing consciousness about the value of incorporating data from real world evidence (RWE) into clinical decision making. Information from real world sources such

The Future of Glaucoma Therapy? Microneedles and the Reduction of Intraocular Pressure

The Future of Glaucoma Therapy? Microneedles and the Reduction of Intraocular Pressure Around 75 million people suffer from glaucoma, making it the world’s leading eye disorder that causes irreversible blindness. Vision loss in glaucoma patients is often accompanied by the dysfunction of the retinal ganglion cell axons. This is believed to

Involvement of Ocular Surface in Graft‐Versus‐Host Disease:  A Review