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Hypertonic and Normal Saline Infusion Calculator

Patient weight:        
Current  Sodium (Na+)  level:  meq/L

Hypertonic Saline (3%) calculator

Hypertonic saline is usually reserved for severe hyponatremia (sodium < 115 meq/L). This calculator targets a level of 120 or 125 meq/L and determines the rate necessary to increase the serum sodium at 0.5 meq/L/hr.  Look below for a review of hyponatremia. In severe cases, the maximum sodium increase within the first 24 hours should not exceed 10 to 12 meq/liter in order to reduce the risk of CNS lesions and/or pulmonary edema.

Target sodium level using 3% saline 

Normal Saline (0.9%) Infusion Calculator

Alternatively, in mild to moderate hyponatremia (serum sodium: 125-134 meq/L), a normal saline infusion is preferred. 
Target Na+ level  
Maximum rate of increase:  

Estimated Body Water Compartment Volumes

 -For patient data entered above

Determine the approximate compartmental volume increases utilizing various maintenance solutions:   
Select  solution:    Volume (ml):  


The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user's use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. Read the disclaimer