Streptococcus anginosus group

Background:

Streptococci
———————————————————
>Streptococcus anginosus group (formerly Streptococcus milleri)led
   ‘Viridans streptococci’: 
     1] Streptococcus intermedius
     2] Streptococcus anginosus
     3] Streptococcus constellatus
>Streptococcus pneumoniae
>Streptobacillus moniliformis
>Streptococcus pyogenes (Groups A, B, C, G, F)
>Streptococcus agalactiae  (Group B streptococcus)

 Streptococcus anginosus group

  • -May be beta-hemolytic or nonhemolytic.
  • -Part of the human bacteria flora  (cultures obtained from mouth, throat, feces, and vagina, other). 
  • Several possible infections are possible based on the frequency of occurence.
  • -Several antimicrobial resistant strains exist.
  • Most strains studied have been shown to be largely susceptible to beta-lactam agents e.g. penicillins, cephalosporins
  • Sulfonamides have no activity.
  • Most strains are resistant to aminoglycosides

 

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Therapy:

Important considerations:  The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions.   Generally, the most common agents/regimens are listed first.    Listed dosages may need to be adjusted for renal dysfunction.

  1. Penicillin VK 500mg orally every 6 hours
  2. Penicillin G 2-4 million units IV q4-6h
  3. Cephalexin 500mg orally every 6 hours
  4. Ceftriaxone 1-2 grams IV q24h
  5. Vancomycin 1 gram  ivpb q12h (patient-specific dosing required)

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user’s use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. Read the disclaimer