Chlamydophila pneumoniae

Background:

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Atypical Organisms
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>Chlamydophila pneumoniae led
>Chlamydophila psittaci
>Coxiella burnetii
>Legionella species ( L. pneumophila)
>Mycoplasma pneumonia

Chlamydophila pneumoniae 

  • -(formally known as Chlamydia pneumoniae)
  • -obligate intracellular bacterium (must infect another cell to reproduce)
  • -major cause of pneumonia.
  • -small gram negative bacterium (0.2 to 1 µm).
  • -undergoes several transformations during its life cycle.
  • -categorized as an “atypical pneumonia” because its treatment and diagnosis are different from historically recognized causes, such as S. pneumoniae.

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Therapy:

Important considerations:  The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions.   Generally, the most common agents/regimens are listed first. Adjust length of therapy based on clinical course.  Generally slow response to therapy and in some cases requires a second course of treatment.

  1. Doxycycline 100mg orally or IV twice daily x 7-10 days
  2. Azithromycin  500mg orally x 1 then 250mg  once daily for 4 days
  3. Clarithromycin 500mg orally twice daily x 7-14 days
  4. Levofloxacin 750 mg IV/PO once daily  x 7-14 days
  5. Moxifloxacin 400mg orally/IV once daily x 7-14 days

Disclaimer

The authors make no claims of the accuracy of the information contained herein; and these suggested doses are not a substitute for clinical judgment. Neither GlobalRPh Inc. nor any other party involved in the preparation of this program shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any user’s use of or reliance upon this material.PLEASE READ THE DISCLAIMER CAREFULLY BEFORE ACCESSING OR USING THIS SITE. BY ACCESSING OR USING THIS SITE, YOU AGREE TO BE BOUND BY THE TERMS AND CONDITIONS SET FORTH IN THE DISCLAIMER. Read the disclaimer