Warfarin Dose Estimation Calculator

WARFARIN DOSE PREDICTION EQUATION

Patient Parameters

Age: Specify race:
Height: Weight:

Target INR

Target INR:

Concomitant conditions

Patient receiving amiodarone:

Smoker:
DVT or PE present?:

Equations Used:

BSA

1] (Weight) kg^0.425 x (Height) cm^0.725 x 0.007184 = BSA in M²

Reference: DuBois D, DuBois DF. A formula to estimate the approximate surface area if height and weight be known. Arch Int Med 1916;17:863-71.

Warfarin Dose Prediction

2]   exp [0.613 + (0.425 x BSA) - (0.0075 x age) + (0.156 x African-American race)
            + (0.216 x target INR) - (0.257 x amiodarone) + (0.108 x smokes)
                + 0.0784 x DVT/PE ]

Reference: Gage BF, Eby C, Johnson JA, Deych E, Rieder MJ, et al. Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin. Clin Pharmacol Ther. 2008 Sep;84(3):326-31. Epub 2008 Feb 27.

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