Staphylococcus saprophyticus


>Staphylococcus Coagulase-negative species:
     1] Staph epidermidis
     2] Staph. haemolyticus
     3] Staph lugdunensis
     4] Staph saprophyticus Led
     5] Staph hominis
     6] Staph capitis

Staphylococcus saprophyticus:

  • gram positive and coagulase-negative species of Staphylococcus bacteria.
  • Often implicated in urinary tract infections (10-20% of UTIs).
  • In females between the ages of about 17-27 it is the second most common causative agent of acute UTIs, after Escherichia coli.
  • Phosphatase-negative, urease- and lipase-positive.


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Important considerations:  The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions.   Generally, the most common agents/regimens are listed first.   Listed dosages may need to be adjusted for renal dysfunction.

  1. Bactrim DS (TMP-SMX)  po bid
  2. Cephalexin 500mg orally every 6 hours
  3. Augmentin 875/125 mg orally twice daily
  4. Levofloxacin 500 mg IV/PO once daily
  5. Ciprofloxacin 250-500 mg orally or 200-400mg IV  q12h.
  6. Norfloxacin 400mg orally twice daily.
Staphylococcus saprophyticus