Staphylococcus Saprophyticus

Staphylococcus saprophyticus

Background:

>Staphylococcus Coagulase-negative species:
     1] Staph epidermidis
     2] Staph. haemolyticus
     3] Staph lugdunensis
     4] Staph saprophyticus

5] Staph hominis
6] Staph capitis

Staphylococcus saprophyticus:

gram positive and coagulase-negative species of Staphylococcus bacteria.
Often implicated in urinary tract infections (10-20% of UTIs).
In females between the ages of about 17-27 it is the second most common causative agent of acute UTIs, after Escherichia coli.
Phosphatase-negative, urease- and lipase-positive.

Therapy:

Important considerations: The choice of an agent should be based on local antimicrobial sensitivities, site of infection, cost, and comorbid conditions. Generally, the most common agents/regimens are listed first. Listed dosages may need to be adjusted for renal dysfunction.

Bactrim DS (TMP-SMX) po bid
Cephalexin 500mg orally every 6 hours
Augmentin 875/125 mg orally twice daily
Levofloxacin 500 mg IV/PO once daily
Ciprofloxacin 250-500 mg orally or 200-400mg IV q12h.
Norfloxacin 400mg orally twice daily.