For the topical treatment of patients with stable plaque psoriasis.
DOSAGE AND ADMINISTRATION
Generally, it is recommended that Zithranol-RR cream be applied once a day. Anthralin is known to be a
potential skin irritant. The irritant potential of anthralin is directly related to the strength being used, the
time of contact, and each patient’s individual tolerance. Where the response to anthralin treatment has not
previously been established, commence treatment using a short contact time (5 – 15 min.) for at least one
week. When a short contact time is used initially, it can be increased stepwise to thirty minutes before
removing the cream by washing or showering. The optimal period of contact will vary according to the
patient’s response to treatment.
For The Skin
Apply sparingly to the psoriatic lesions avoiding normal skin and rub gently and carefully
into the skin. Avoid applying an excessive quantity which may cause unnecessary soiling and staining of
the clothing and/or bed linen. At the end of each period of treatment, rinse the skin thoroughly with cool
to lukewarm water before washing with soap. The margins of the lesions may gradually become stained
purple/brown as treatment progresses, but this will disappear after cessation of treatment.
For The Scalp
Wash the hair with shampoo, rinse with water and apply Zithranol-RR cream while the
hair is still damp. Rub the cream well into the psoriatic lesions. Keep Zithranol-RR cream away from
the eyes. Care should be taken to avoid application to uninvolved scalp margins. Remove any unintended
residue which may be deposited behind the ears. At the end of each period of contact, rinse hair and
scalp thoroughly with cool to lukewarm water and then shampoo the hair and scalp to remove any
surplus cream. This treatment may be repeated on alternate days if necessary.
Zithranol-RR (anthralin) microcrystalline encapsulated cream, 1.2% is supplied in tubes.
45g -NDC 42783-101-45
15g -NDC 42783-101-15
Store at controlled room temperature 59°F to 86°F (15°C to 30°C).
Manufactured for: Elorac, Inc.Vernon Hills, IL 60061. Revised: January 2010.