Librium (chlordiazepoxide) is indicated for the management of anxiety disorders or for the short
term relief of symptoms of anxiety, withdrawal" symptoms of acute alcoholism,
and preoperative apprehension and anxiety. Anxiety or tension associated with
the stress of everyday life usually does not require treatment with an anxiolytic.
The effectiveness of Librium (chlordiazepoxide) in long-term use, that is, more than 4 months,
has not been assessed by systematic clinical studies. The physician should periodically
reassess the usefulness of the drug for the individual patient.
DOSAGE AND ADMINISTRATION
Because of the wide range of clinical indications for Librium (chlordiazepoxide) , the optimum
dosage varies with the diagnosis and response of the individual patient. The
dosage, therefore, should be individualized for maximum beneficial effects.
|| USUAL DAILY DOSE
| Relief of Mild and Moderate Anxiety Disorders and Symptoms
|| 5 mg or 10 mg, 3 or 4 times daily
| Relief of Severe Anxiety Disorders and Symptoms of Anxiety
|| 20 mg or 25 mg, 3 or 4 times daily
| Geriatric Patients, or in the presence of debilitating
|| 5 mg, 2 to 4 times daily
Preoperative Apprehension and Anxiety: On days preceding surgery, 5 to 10 mg
orally, 3 or 4 times daily. If used as preoperative medication, 50 to 100 mg
IM* 1 hour prior to surgery.
| PEDIATRIC PATIENTS
|| USUAL DAILY DOSE
| Because of the varied response of pediatric patients to
CNS-acting drugs, therapy should be initiated with the lowest dose and
increased as required. Since clinical experience in pediatric patients
under 6 years of age is limited, the use of the drug in this age group
is not recommended.
|| 5 mg, 2 to 4 times daily (may be increased in some pediatric
patients to 10 mg, 2 to 3 times daily)
For the relief of withdrawal symptoms of acute alcoholism, the parenteral form*
is usually used initially. If the drug is administered orally, the suggested
initial dose is 50 to 100 mg, to be followed by repeated doses as needed until
agitation is controlled up to 300 mg per day. Dosage should then be reduced
to maintenance levels.
* See package insert for Injectable Librium (chlordiazepoxide HCI).
Librium (chlordiazepoxide HCI) Capsules are available in the following presentations: