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AMINOSYN® II 5%
in 25% Dextrose Injection
AN AMINO ACID INJECTION IN DEXTROSE INJECTION
NOTE: These solutions are hypertonic. See WARNINGS
and PRECAUTIONS.
Nutrimix® Dual-chamber Flexible Container
The Upper Chamber Contains 500 mL of Aminosyn II 10% (An Amino Acid Injection)
The Lower Chamber Contains 500 mL of 50% Dextrose Injection, USP
Upper Chamber: Contains 500 mL of Aminosyn II 10% (an amino acid injection) — a sterile, nonpyrogenic solution for intravenous infusion. The formulation is described in the table below.
Lower Chamber: Contains 500 mL of 50% Dextrose Injection, USP — a sterile, nonpyrogenic, hypertonic solution of Dextrose, USP in water for injection. The table below indicates the characteristics of this concentrated solution.
The container must be used only after removing the clamp and thoroughly mixing the contents of the two chambers. The solution resulting from mixing the contents of the upper and lower chamber contains 5% amino acids in 25% dextrose. Mixing the contents of the upper and lower chambers yields a concentrated source of amino acids and carbohydrate calories for intravenous infusion. Headspace contains Nitrogen gas. The composition of this admixture is described in the table below.
| Solution Composition per 100 mL | |||
| Upper Chamber |
Lower Chamber |
Admixture | |
| Dextrose, hydrous (g) | 50 | 25 | |
| Essential Amino Acids (mg) | |||
| Isoleucine | 660 | 330 | |
| Leucine | 1000 | 500 | |
| Lysine (as acetate salt)* | 1050 | 525 | |
| Methionine | 172 | 86 | |
| Phenylalanine | 298 | 149 | |
| Threonine | 400 | 200 | |
| Tryptophan | 200 | 100 | |
| Valine | 500 | 250 | |
| Nonessential Amino Acids (mg) | |||
| Alanine | 993 | 496 | |
| Arginine | 1018 | 509 | |
| L-Aspartic Acid | 700 | 350 | |
| L-Glutamic Acid | 738 | 369 | |
| Glycine | 500 | 250 | |
| Histidine | |||
