Ticarcillin Clav.acid

Usual Dosing (Adults)

Ticarcillin
3 or 4 grams every 4 or 6 hours (200 to 300 milligrams/kilogram/day)

Ticarcillin/Clavulanate
Timentin ®
3.1 grams q4-6h.

Renal Dosing

Ticarcillin
[>60 ml/min]: No change
[30-60]: 2 grams q4h.
[10-30]: 2 grams q8h
[<10]: 1-2 grams q12h.
[<10 and hepatic dysfx]: 2g q24h

Ticarcillin/Clavulanate
Timentin ®
[>60 ml/min]: no change
[30-60]: 2 gm q4h or 3.1gm q8h
[10-30]: 2 gm q8h or 3.1 gm q12h
[<10]: 2 grams q12h
[<10 + hepatic dysfcn]: 2g q24h.

Hemodialysis

Ticarcillin
Hemo: 2 grams q12h + supplemental dose (2-3 grams) after dialysis.

Ticarcillin/Clavulanate - Timentin ®
Hemo:
2 grams q12h + additional 3.1 g after each dialysis.

PD: 3.1 grams q12h

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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