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Usual Dosing (Adults)

300mg po qhs or 150mg po bid.
Maintenance: 150mg po qhs.
Erosive esophagitis: 150mg po q6h.
(IV/IM): 50mg q6-8h. Continuous infusion: 6.25mg/hr (higher doses are possible).

Renal Dosing

dialysis [>50 ml/min]: No changes.

[0 – 49]: 150mg po q24h or 50mg IV q18-24h. If needed, interval may be increased to q12h if patient is carefully monitored.


dialysis Hemodialysis: 
150mg po q24h or 50mg IV q18-24h. Schedule doses after dialysis on dialysis days. 


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.


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